Efaproxiral
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- $49 - $1675
- Product name: Efaproxiral
- CAS: 131179-95-8
- MF: C20H22NO4.Na
- MW: 341.4
- EINECS:1806241-263-5
- MDL Number:MFCD00899086
- Synonyms:2-(4-(((3,5-dimethylanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid;Efaproxiral;Efaproxiral free acid;faproxiral;EFAPROXIRALUM;2-[4-(3,5-Dimethylphenylcarbamoylmethyl)phenoxy]-2-methylpropionic acid;EFAPROXIRAL;EFAPROXIRAL FREE ACID;FAPROXIRAL;Propanoic acid, 2-[4-[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methyl-
12 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- Crysdot
- TRC
Package
- 50mg
- 100mg
- 250MG
- 500mg
- 1g
- 2.5G
- ManufacturerAK Scientific
- Product number5787AA
- Product description2-(4-(2-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoicacid
- Packaging1g
- Price$694
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005193
- Product descriptionEFAPROXIRA 95.00%
- Packaging250MG
- Price$527.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005193
- Product descriptionEFAPROXIRA 95.00%
- Packaging1G
- Price$910
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005193
- Product descriptionEFAPROXIRA 95.00%
- Packaging2.5G
- Price$1675
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28294
- Product descriptionEfaproxiral
- Packaging100mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28294
- Product descriptionEfaproxiral
- Packaging250mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28294
- Product descriptionEfaproxiral
- Packaging500mg
- Price$302
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28294
- Product descriptionEfaproxiral
- Packaging1g
- Price$535
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-4950
- Product descriptionEfaproxiral 99.42%
- Packaging50mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD12154506
- Product descriptionEfaproxiral 98+%
- Packaging50mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD12154506
- Product descriptionEfaproxiral 98+%
- Packaging100mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberE415000
- Product descriptionEfaproxiral
- Packaging250mg
- Price$175
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5787AA | 2-(4-(2-((3,5-Dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoicacid | 1g | $694 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005193 | EFAPROXIRA 95.00% | 250MG | $527.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005193 | EFAPROXIRA 95.00% | 1G | $910 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005193 | EFAPROXIRA 95.00% | 2.5G | $1675 | 2021-12-16 | Buy |
| Cayman Chemical | 28294 | Efaproxiral | 100mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 28294 | Efaproxiral | 250mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 28294 | Efaproxiral | 500mg | $302 | 2024-03-01 | Buy |
| Cayman Chemical | 28294 | Efaproxiral | 1g | $535 | 2024-03-01 | Buy |
| ChemScene | CS-4950 | Efaproxiral 99.42% | 50mg | $84 | 2021-12-16 | Buy |
| Crysdot | CD12154506 | Efaproxiral 98+% | 50mg | $49 | 2021-12-16 | Buy |
| Crysdot | CD12154506 | Efaproxiral 98+% | 100mg | $63 | 2021-12-16 | Buy |
| TRC | E415000 | Efaproxiral | 250mg | $175 | 2021-12-16 | Buy |
Properties
Melting point :48-50°C
Boiling point :554.5±50.0 °C(Predicted)
Density :1.202±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :3.26±0.10(Predicted)
color :Off-White to Tan
Boiling point :554.5±50.0 °C(Predicted)
Density :1.202±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :3.26±0.10(Predicted)
color :Off-White to Tan
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Efaproxiral is an allosteric hemoglobin (Hb) modifier that reduces the affinity of Hb for oxygen, increasing the diffusion of oxygen from blood to tissue. In isolated human whole blood, efaproxiral (1.75 mM) increases the partial pressure of oxygen at which Hb is 50% saturated (p50) from 26.75 to 38.63 mm Hg and decreases the percent oxyhemoglobin (Hb-O2) saturation from 48 to 33.8% at a partial oxygen pressure (pO2) of 26 mm Hg. Efaproxiral (150 mg/kg) increases tumor pO2 from 5.2 to 13.1 mm Hg 30 minutes after administration in a RIF-1 mouse fibrosarcoma flank tumor model. Efaproxiral (100 μM) enhances radiation-induced cytotoxicity in EMT6 mouse breast cancer cells grown under hypoxic conditions and increases radiosensitization and inhibits tumor growth in a hypoxic Lewis lung tumor mouse model when administered at a dose of 100 mg/kg. It also increases the running capacity of normal mice and mice with left coronary artery (LCA) ligation-induced myocardial infarction (MI) when administered at a dose of 150 mg/kg.Related product price
- beta-Alanine
$5-1733 - Diethoxydimethylsilane
$20-630 - Efaproxiral sodium
$17-1000
