Efavirenz
|
- $25 - $2400
- Product name: Efavirenz
- CAS: 154598-52-4
- MF: C14H9ClF3NO2
- MW: 315.67
- EINECS:620-492-6
- MDL Number:MFCD05662344
- Synonyms:(S)-6-Chloro-4-(cyclopropylethynyl)-1，4-dihydro-4-(trifluoromethyl) 2H-3，1-benzoxazin-2-one;(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;Efavirenz (200 mg);(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoroMethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoroMethyl)-, (4S)-;efavuirenz;Efavirenz solution;(S)-6-CHLORO-4-(CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-1H-BENZO[D][1,3]OXAZIN-2(4H)-ONE
42 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Chemtos
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 10mM(in 1mL DMSO)
- 0.1g
- 200mg
- 250mg
- 500mg
- 1g
- 1ml
- 2g
- 5G
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3751-M050
- Product descriptionEfavirenz ≥98%(HPLC)
- Packaging50mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1192
- Product descriptionEfavirenz 98%
- Packaging0.1g
- Price$630
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ95133
- Product descriptionEfavirenz
- Packaging1g
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1119
- Product descriptionEfavirenz
- Packaging50mg
- Price$335
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1119
- Product descriptionEfavirenz
- Packaging25mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1119
- Product descriptionEfavirenz
- Packaging10mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1119
- Product descriptionEfavirenz
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3125
- Product descriptionEfavirenz-DMP-266|L-743,726 99%
- Packaging10mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3125
- Product descriptionEfavirenz-DMP-266|L-743,726 99%
- Packaging50mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134784
- Product descriptionEfavirenz >99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134784
- Product descriptionEfavirenz >99%
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134784
- Product descriptionEfavirenz >99%
- Packaging1g
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC30275
- Product description(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
- Packaging100mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC30275
- Product description(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
- Packaging250mg
- Price$235
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC30275
- Product description(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
- Packaging500mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC30275
- Product description(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
- Packaging1g
- Price$550
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3751-M050 | Efavirenz ≥98%(HPLC) | 50mg | $110 | 2021-12-16 | Buy |
| AHH | API-1192 | Efavirenz 98% | 0.1g | $630 | 2021-12-16 | Buy |
| AK Scientific | J95133 | Efavirenz | 1g | $25 | 2021-12-16 | Buy |
| ApexBio Technology | B1119 | Efavirenz | 50mg | $335 | 2021-12-16 | Buy |
| ApexBio Technology | B1119 | Efavirenz | 25mg | $189 | 2021-12-16 | Buy |
| ApexBio Technology | B1119 | Efavirenz | 10mg | $80 | 2021-12-16 | Buy |
| ApexBio Technology | B1119 | Efavirenz | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| Axon Medchem | Axon3125 | Efavirenz-DMP-266|L-743,726 99% | 10mg | $66 | 2021-12-16 | Buy |
| Axon Medchem | Axon3125 | Efavirenz-DMP-266|L-743,726 99% | 50mg | $132 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134784 | Efavirenz >99% | 100mg | $510 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134784 | Efavirenz >99% | 250mg | $765 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134784 | Efavirenz >99% | 1g | $1504.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC30275 | (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one | 100mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC30275 | (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one | 250mg | $235 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC30275 | (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one | 500mg | $360 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC30275 | (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one | 1g | $550 | 2021-12-16 | Buy |
Properties
Melting point :139-141°C
Boiling point :340.6±42.0 °C(Predicted)
alpha :D20 -84.7° (c = 0.005 g/ml in CH3Cl); D25 -94.1° (c = 0.300 in methanol)
Density :1.53±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :10.2(at 25℃)
form :powder or crystals
color :white to beige
optical activity :[α]/D -90 to -100°, c = 1 in methanol
Water Solubility :8mg/L(temperature not stated)
λmax :247nm(MeOH)(lit.)
Merck :14,3521
BCS Class :4
EPA Substance Registry System :2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)- (154598-52-4)
Boiling point :340.6±42.0 °C(Predicted)
alpha :D20 -84.7° (c = 0.005 g/ml in CH3Cl); D25 -94.1° (c = 0.300 in methanol)
Density :1.53±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :10.2(at 25℃)
form :powder or crystals
color :white to beige
optical activity :[α]/D -90 to -100°, c = 1 in methanol
Water Solubility :8mg/L(temperature not stated)
λmax :247nm(MeOH)(lit.)
Merck :14,3521
BCS Class :4
EPA Substance Registry System :2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)- (154598-52-4)
Safety Information
| Symbol(GHS): |
  
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Efavirenz is an NNRTI that prevents RNA plus-strand initiation with an IC50 value of 17 nM. Efavirenz also inhibits the late stages of HIV-1 replication by interfering with HIV-1 Gag-Pol polyprotein processing. It has been used in combination therapy with drugs directed at the treatment of opportunistic infections such as HIV and cancer.More related product prices
Trimethylsilylacetylene 5-Methyl-1H-benzotriazole Propiconazole 2-METHYL-1,3-PROPANEDIOL Eptifibatide rac 8-Hydroxy Efavirenz Efavirenz Related Compound B (15 mg) ((S,E)-6-Chloro-4-(2-Cyclopropylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) 391860-73-4 [4-Chloro-2-[(1S)-3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-propynyl)phenyl]carbamic Acid Methyl Ester (1S,2R)-N-TOSYLEPHEDRINE 123620-80-4 rac 5-Chloro-a-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-a-(trifluoromethyl)-benzenemethanol (R)-5-Chloro-α-(cyclopropylethynyl)-2-amino-α-(trifluoromethyl) benzenemethanol 99727-20-5Related product price
- Trimethylsilylacetylene
$9-725 - Poly(vinyl alcohol)
$0-4353.77 - 5-Methyl-1H-benzotriazole
$10-1070
Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Shaanxi Yikanglong Biotechnology Co., Ltd.
Biochempartner
Shenzhen Nexconn Pharmatechs Ltd
Hubei Jusheng Technology Co.,Ltd.
