Erlotinib D6 HCl
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- $145 - $1871.1
- Product name: Erlotinib D6 HCl
- CAS: 1189953-78-3
- MF: C22H18ClD6N3O4
- MW: 435.933630668
- EINECS:
- MDL Number:MFCD09840535
- Synonyms:Erlotinib D6;Erlotinib Hydrochloride Impurity G;[2H6]-Erlotinib Hydrochloride;CP-358774 D6 hydrochloride;NSC 718781 D6 hydrochloride;OSI-774 D6 hydrochloride;Erlotiniβ-d6 Hydrochloride
4 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- TRC
Package
- 1mg
- 10MG
- ManufacturerAK Scientific
- Product number7728DG
- Product descriptionErlotinibD6Hydrochloride
- Packaging1mg
- Price$409
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0006809
- Product descriptionERLOTINIB-D6-HYDROCHLORIDE 95.00%
- Packaging10MG
- Price$1871.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22101
- Product descriptionErlotinib-d6 (hydrochloride) ≥99% deuterated forms (d1-d6)
- Packaging1mg
- Price$279
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberE625002
- Product descriptionErlotinib-d6Hydrochloride
- Packaging1mg
- Price$145
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7728DG | ErlotinibD6Hydrochloride | 1mg | $409 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0006809 | ERLOTINIB-D6-HYDROCHLORIDE 95.00% | 10MG | $1871.1 | 2021-12-16 | Buy |
| Cayman Chemical | 22101 | Erlotinib-d6 (hydrochloride) ≥99% deuterated forms (d1-d6) | 1mg | $279 | 2024-03-01 | Buy |
| TRC | E625002 | Erlotinib-d6Hydrochloride | 1mg | $145 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO: slightly, heated,Methanol: slightly soluble
form :A solid
color :White to off-white
solubility :DMSO: slightly, heated,Methanol: slightly soluble
form :A solid
color :White to off-white
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Erlotinib-d6 (hydrochloride) contains six deuterium atoms located on the methoxy group. It is intended for use as an internal standard for the quantification of erlotinib by GC- or LC-MS. Erlotinib is a tyrosine kinase inhibitor that acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 μM) and JAK2 mutant JAK2V617F (IC50 = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. Formulations containing erlotinib are used to treat certain forms of cancer, including non-small cell lung cancer.More related product prices
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$81-1940
