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ChemicalBook >> CAS DataBase List >> Futibatinib

Futibatinib

Futibatinib price.
  • $57 - $1900
  • Product name: Futibatinib
  • CAS: 1448169-71-8
  • MF: C22H22N6O3
  • MW: 418.45
  • EINECS:
  • MDL Number:MFCD29037352
  • Synonyms:FGFR-IN-1;FGFR-IN-1;FUTIBATINIB;TAS-120;FUTIBATINIB;TAS120;TAS-120 (Futibatinib);CS-2681;CS-2344;2-Propen-1-one, 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-;1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-2-propen-1-one
12 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number9745DU
  • Product descriptionFutibatinib
  • Packaging1mg
  • Price$197
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21136
  • Product descriptionTAS 120 ≥98%
  • Packaging500μg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21136
  • Product descriptionTAS 120 ≥98%
  • Packaging1mg
  • Price$89
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21136
  • Product descriptionTAS 120 ≥98%
  • Packaging5mg
  • Price$356
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21136
  • Product descriptionTAS 120 ≥98%
  • Packaging10mg
  • Price$656
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6031
  • Product descriptionFutibatinib 98.80%
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6031
  • Product descriptionFutibatinib 98.80%
  • Packaging10mg
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6031
  • Product descriptionFutibatinib 98.80%
  • Packaging50mg
  • Price$880
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11089
  • Product descriptionTAS-120(Futibatinib) >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11089
  • Product descriptionTAS-120(Futibatinib) >98%
  • Packaging250mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11089
  • Product descriptionTAS-120(Futibatinib) >98%
  • Packaging1g
  • Price$1900
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT773508
  • Product descriptionTAS-120
  • Packaging1mg
  • Price$90
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9745DU Futibatinib 1mg $197 2021-12-16 Buy
Cayman Chemical 21136 TAS 120 ≥98% 500μg $57 2024-03-01 Buy
Cayman Chemical 21136 TAS 120 ≥98% 1mg $89 2024-03-01 Buy
Cayman Chemical 21136 TAS 120 ≥98% 5mg $356 2024-03-01 Buy
Cayman Chemical 21136 TAS 120 ≥98% 10mg $656 2024-03-01 Buy
ChemScene CS-6031 Futibatinib 98.80% 5mg $180 2021-12-16 Buy
ChemScene CS-6031 Futibatinib 98.80% 10mg $310 2021-12-16 Buy
ChemScene CS-6031 Futibatinib 98.80% 50mg $880 2021-12-16 Buy
DC Chemicals DC11089 TAS-120(Futibatinib) >98% 100mg $550 2021-12-16 Buy
DC Chemicals DC11089 TAS-120(Futibatinib) >98% 250mg $950 2021-12-16 Buy
DC Chemicals DC11089 TAS-120(Futibatinib) >98% 1g $1900 2021-12-16 Buy
TRC T773508 TAS-120 1mg $90 2021-12-16 Buy

Properties

Boiling point :733.8±60.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:38.0(Max Conc. mg/mL);90.81(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);71.69(Max Conc. mM)
DMF:PBS (pH 7.2) (1:5):0.16(Max Conc. mg/mL);0.38(Max Conc. mM)
Ethanol:0.5(Max Conc. mg/mL);1.19(Max Conc. mM) form :A crystalline solid
pka :3.60±0.30(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Futibatinib is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. Futibatinib selectively and irreversibly binds to and inhibits FGFR, which may result in the inhibition of both the FGFR-mediated signal transduction pathway and tumor cell proliferation, and increased cell death in FGFR-overexpressing tumor cells. FGFR is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival and its expression is upregulated in many tumor cell types.

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