GSK2656157
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- $24 - $2839
- Product name: GSK2656157
- CAS: 1337532-29-2
- MF: C23H21FN6O
- MW: 416.45
- EINECS:-0
- MDL Number:MFCD27997885
- Synonyms:GSK2656157;1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone;5-[4-Fluoro-1-[(6-methyl-2-pyridinyl)acetyl]-2,3-dihydro-1H-indol-5-yl]-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine GSK2656157;1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyrid;GSK2656157(GSK-2656157);GSK2656157; GSK 2656157; GSK-2656157.;1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethan-1-one GSK2656157;PERK inhibitor GS2656157
30 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2448AH
- Product descriptionGSK2656157
- Packaging250mg
- Price$1260
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA184177
- Product descriptionGSK2656157 98+%
- Packaging1mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA184177
- Product descriptionGSK2656157 98+%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA184177
- Product descriptionGSK2656157 98+%
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA184177
- Product descriptionGSK2656157 98+%
- Packaging50mg
- Price$257
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA184177
- Product descriptionGSK2656157 98+%
- Packaging100mg
- Price$452
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002509
- Product description1-(5-(4-AMINO-7-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-4-FLUOROINDOLIN-1-YL)-2-(6-METHYLPYRIDIN-2-YL)ETHANONE 95.00%
- Packaging5MG
- Price$495.58
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2175
- Product descriptionGSK2656157
- Packaging10mM(in 1mL DMSO)
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60284
- Product descriptionGSK2656157
- Packaging10mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146228
- Product descriptionGSK2656157 >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146228
- Product descriptionGSK2656157 >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146228
- Product descriptionGSK2656157 >98%
- Packaging1g
- Price$2839
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17372
- Product descriptionGSK2656157 ≥98%
- Packaging5mg
- Price$47
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17372
- Product descriptionGSK2656157 ≥98%
- Packaging10mg
- Price$87
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17372
- Product descriptionGSK2656157 ≥98%
- Packaging25mg
- Price$206
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17372
- Product descriptionGSK2656157 ≥98%
- Packaging50mg
- Price$360
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2448AH | GSK2656157 | 250mg | $1260 | 2021-12-16 | Buy |
| Ambeed | A184177 | GSK2656157 98+% | 1mg | $24 | 2021-12-16 | Buy |
| Ambeed | A184177 | GSK2656157 98+% | 5mg | $50 | 2021-12-16 | Buy |
| Ambeed | A184177 | GSK2656157 98+% | 10mg | $70 | 2021-12-16 | Buy |
| Ambeed | A184177 | GSK2656157 98+% | 50mg | $257 | 2021-12-16 | Buy |
| Ambeed | A184177 | GSK2656157 98+% | 100mg | $452 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002509 | 1-(5-(4-AMINO-7-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-4-FLUOROINDOLIN-1-YL)-2-(6-METHYLPYRIDIN-2-YL)ETHANONE 95.00% | 5MG | $495.58 | 2021-12-16 | Buy |
| ApexBio Technology | B2175 | GSK2656157 | 10mM(in 1mL DMSO) | $99 | 2021-12-16 | Buy |
| Arctom | CFN60284 | GSK2656157 | 10mg | $168 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146228 | GSK2656157 >98% | 100mg | $690.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146228 | GSK2656157 >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146228 | GSK2656157 >98% | 1g | $2839 | 2021-12-16 | Buy |
| Cayman Chemical | 17372 | GSK2656157 ≥98% | 5mg | $47 | 2024-03-01 | Buy |
| Cayman Chemical | 17372 | GSK2656157 ≥98% | 10mg | $87 | 2024-03-01 | Buy |
| Cayman Chemical | 17372 | GSK2656157 ≥98% | 25mg | $206 | 2024-03-01 | Buy |
| Cayman Chemical | 17372 | GSK2656157 ≥98% | 50mg | $360 | 2024-03-01 | Buy |
Properties
Melting point :194-196°C
Boiling point :744.6±60.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (10 mg/ml with warming)
form :solid
pka :5.32±0.30(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Boiling point :744.6±60.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (10 mg/ml with warming)
form :solid
pka :5.32±0.30(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
GSK2656157 (1337532-29-2) is a potent (IC50 = 0.9 nM) and selective (over 300 kinases) inhibitor of protein kinase RNA-like endoplasmic reticulum kinase (PERK).1,2? Inhibited growth of multiple human tumor xenografts in mice. GSK2656157 has also been found to potently inhibit RIPK1 (IC50 = 69 nM) and TNF-mediated RIPK1 kinase-dependent cell death in mouse embryonic fibroblasts.3 It prevented the loss of dendritic spines and rescued memory deficits after traumatic brain injury.4? GSK2656157 also enhanced glucose-stimulated insulin secretion in a mouse model of type 2 diabetes mellitus.5More related product prices
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