HYDROXYFLUTAMIDE
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- $5 - $1985
- Product name: HYDROXYFLUTAMIDE
- CAS: 52806-53-8
- MF: C11H11F3N2O4
- MW: 292.21
- EINECS:
- MDL Number:MFCD00563126
- Synonyms:2-hydroxy-2-methyl-n-(4-nitro-3-(trifluoromethyl)phenyl)-propanamid ;hydroxyniphtholide ;2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propionamide;Hydroxy-Flutamide(Flutamide metabolite);5-Hydroxyflutamide, 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide, ;5-HYDROXYFLUTAMIDE;HYDROXYFLUTAMIDE (2-HYDROXY-2-METHYL-N-{4''-NITRO-3''-(TRIFLUOROMETHYL)PHENYL}PROPANAMIDE);α,α,α-Trifluoro-2-Methyl-4'-nitro-M- lactotoluidide
34 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chem-Impex
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 0.1g
- 100mg
- 250mg
- 1g
- 5g
- 10g
- ManufacturerAHH
- Product numberMT-15089
- Product descriptionHydroxyflutamide 95%
- Packaging0.1g
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX6072
- Product descriptionHydroxyflutamide
- Packaging5mg
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX6072
- Product descriptionHydroxyflutamide
- Packaging10mg
- Price$177
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA754229
- Product descriptionHydroxyflutamide 98+%
- Packaging25mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA754229
- Product descriptionHydroxyflutamide 98+%
- Packaging100mg
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA754229
- Product descriptionHydroxyflutamide 98+%
- Packaging250mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA754229
- Product descriptionHydroxyflutamide 98+%
- Packaging1g
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA754229
- Product descriptionHydroxyflutamide 98+%
- Packaging5g
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA754229
- Product descriptionHydroxyflutamide 98+%
- Packaging10g
- Price$344
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007072
- Product descriptionHYDROXYFLUTAMIDE 95.00%
- Packaging5MG
- Price$193.6
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007072
- Product descriptionHYDROXYFLUTAMIDE 95.00%
- Packaging10MG
- Price$693
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007072
- Product descriptionHYDROXYFLUTAMIDE 95.00%
- Packaging100MG
- Price$1501.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4721
- Product description2-hydroxyFlutamide
- Packaging25mg
- Price$249
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134531
- Product descriptionHydroxyflutamide (Hydroxyniphtholide) >99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134531
- Product descriptionHydroxyflutamide (Hydroxyniphtholide) >99%
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134531
- Product descriptionHydroxyflutamide (Hydroxyniphtholide) >99%
- Packaging1g
- Price$1504.5
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-15089 | Hydroxyflutamide 95% | 0.1g | $750 | 2021-12-16 | Buy |
| AK Scientific | X6072 | Hydroxyflutamide | 5mg | $136 | 2021-12-16 | Buy |
| AK Scientific | X6072 | Hydroxyflutamide | 10mg | $177 | 2021-12-16 | Buy |
| Ambeed | A754229 | Hydroxyflutamide 98+% | 25mg | $5 | 2021-12-16 | Buy |
| Ambeed | A754229 | Hydroxyflutamide 98+% | 100mg | $16 | 2021-12-16 | Buy |
| Ambeed | A754229 | Hydroxyflutamide 98+% | 250mg | $23 | 2021-12-16 | Buy |
| Ambeed | A754229 | Hydroxyflutamide 98+% | 1g | $58 | 2021-12-16 | Buy |
| Ambeed | A754229 | Hydroxyflutamide 98+% | 5g | $208 | 2021-12-16 | Buy |
| Ambeed | A754229 | Hydroxyflutamide 98+% | 10g | $344 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007072 | HYDROXYFLUTAMIDE 95.00% | 5MG | $193.6 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007072 | HYDROXYFLUTAMIDE 95.00% | 10MG | $693 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007072 | HYDROXYFLUTAMIDE 95.00% | 100MG | $1501.5 | 2021-12-16 | Buy |
| ApexBio Technology | C4721 | 2-hydroxyFlutamide | 25mg | $249 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134531 | Hydroxyflutamide (Hydroxyniphtholide) >99% | 100mg | $510 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134531 | Hydroxyflutamide (Hydroxyniphtholide) >99% | 250mg | $765 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134531 | Hydroxyflutamide (Hydroxyniphtholide) >99% | 1g | $1504.5 | 2021-12-16 | Buy |
Properties
Melting point :125-130°C
Boiling point :443.8±45.0 °C(Predicted)
Density :1.472
storage temp. :room temp
solubility :DMSO: >10mg/mL
form :powder
pka :12.87±0.70(Predicted)
color :white to tan
Boiling point :443.8±45.0 °C(Predicted)
Density :1.472
storage temp. :room temp
solubility :DMSO: >10mg/mL
form :powder
pka :12.87±0.70(Predicted)
color :white to tan
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
2-hydroxy Flutamide is the major metabolite formed during the metabolism of the non-steroidal antiandrogen flutamide by cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4. Through competitive inhibition of the binding of testosterone to the nuclear androgen receptor (AR; IC50 = ~300-900), 2-hydroxy flutamide blocks the expression of AR target genes and prevents androgen-dependent stabilization of the AR. Compared to flutamide, 2-hydroxy flutamide is a more potent antiandrogen in vivo, demonstrating a higher binding affinity for the AR (0.1% binding affinity relative to dihydrotestosterone) and, thus, is the predominant contributor to the therapeutic effects of flutamide in the treatment of prostate cancer.Related product price
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