Isochlorogenic acid C
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- $60 - $2839
- Product name: Isochlorogenic acid C
- CAS: 57378-72-0
- MF: C25H24O12
- MW: 516.45
- EINECS:
- MDL Number:MFCD10566623
- Synonyms:Isochlorogenic acid C;(1R)-1,3β-Dihydroxy-4α,5α-bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-1β-cyclohexanecarboxylic acid;(1R,3R,4S,5R)-1,5-Dihydroxy-3,4-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1-cyclohexanecarboxylic acid;1β,5α-Dihydroxy-3β,4β-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid;Isochlorogenic acid C(4,5');4,5-Dicaffeoylquinic acid, >99%;Cyclohexanecarboxylic acid, 3,4-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,5-dihydroxy-, (1R,3R,4S,5R)-;(1R,3R,4S,5R)-3,4-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,5-dihydroxycyclohexanecarboxylic acid
27 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberV1561
- Product description4,5-Dicaffeoylquinicacid
- Packaging1mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV1561
- Product description4,5-Dicaffeoylquinicacid
- Packaging10mg
- Price$192
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA117820
- Product description(1R,3R,4S,5R)-3,4-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,5-dihydroxycyclohexanecarboxylicacid 98+%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN90354
- Product descriptionIsochlorogenicacidC(4,5) ≥98%
- Packaging20mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS018901
- Product description(1R,3R,4S,5R)-3,4-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,5-dihydroxycyclohexanecarboxylicacid
- Packaging5mg
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2086
- Product description4,5-Dicaffeoylquinic acid
- Packaging5mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2086
- Product description4,5-Dicaffeoylquinic acid
- Packaging10mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2086
- Product description4,5-Dicaffeoylquinic acid
- Packaging25mg
- Price$295
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2086
- Product description4,5-Dicaffeoylquinic acid
- Packaging100mg
- Price$895
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb104801
- Product descriptionIsochlorogenic acid C(4,5') >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573039
- Product descriptionIsochlorogenic acid C >98%,Standard References Grade
- Packaging100mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573039
- Product descriptionIsochlorogenic acid C >98%,Standard References Grade
- Packaging250mg
- Price$1654.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573039
- Product descriptionIsochlorogenic acid C >98%,Standard References Grade
- Packaging1g
- Price$2839
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64832
- Product description4,5-Dicaffeoylquinic acid
- Packaging2mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64832
- Product description4,5-Dicaffeoylquinic acid
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64832
- Product description4,5-Dicaffeoylquinic acid
- Packaging10mg
- Price$200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | V1561 | 4,5-Dicaffeoylquinicacid | 1mg | $119 | 2021-12-16 | Buy |
| AK Scientific | V1561 | 4,5-Dicaffeoylquinicacid | 10mg | $192 | 2021-12-16 | Buy |
| Ambeed | A117820 | (1R,3R,4S,5R)-3,4-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,5-dihydroxycyclohexanecarboxylicacid 98+% | 5mg | $90 | 2021-12-16 | Buy |
| Arctom | CFN90354 | IsochlorogenicacidC(4,5) ≥98% | 20mg | $138 | 2021-12-16 | Buy |
| Arctom | AS018901 | (1R,3R,4S,5R)-3,4-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,5-dihydroxycyclohexanecarboxylicacid | 5mg | $89 | 2021-12-16 | Buy |
| AvaChem | 2086 | 4,5-Dicaffeoylquinic acid | 5mg | $95 | 2021-12-16 | Buy |
| AvaChem | 2086 | 4,5-Dicaffeoylquinic acid | 10mg | $145 | 2021-12-16 | Buy |
| AvaChem | 2086 | 4,5-Dicaffeoylquinic acid | 25mg | $295 | 2021-12-16 | Buy |
| AvaChem | 2086 | 4,5-Dicaffeoylquinic acid | 100mg | $895 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb104801 | Isochlorogenic acid C(4,5') >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573039 | Isochlorogenic acid C >98%,Standard References Grade | 100mg | $912.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573039 | Isochlorogenic acid C >98%,Standard References Grade | 250mg | $1654.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573039 | Isochlorogenic acid C >98%,Standard References Grade | 1g | $2839 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD64832 | 4,5-Dicaffeoylquinic acid | 2mg | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD64832 | 4,5-Dicaffeoylquinic acid | 5mg | $110 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD64832 | 4,5-Dicaffeoylquinic acid | 10mg | $200 | 2021-12-16 | Buy |
Properties
Boiling point :810.8±65.0 °C(Predicted)
Density :1?+-.0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml; DMSO: 5 mg/ml
form :A solid
pka :3.70±0.50(Predicted)
color :White to off-white
Density :1?+-.0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml; DMSO: 5 mg/ml
form :A solid
pka :3.70±0.50(Predicted)
color :White to off-white
Safety Information
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Description
4,5-Dicaffeoylquinic acid (4,5-DCQA) is a polyphenol originally isolated from G. fagetorum and G. pseudomollugo that has diverse biological activities, including anti-HIV replication, antioxidative, anti-inflammatory, and anti-melanogenic properties. It inhibits HIV-1 integrase 3'' end processing, 3’ end joining, and disintegration with IC50 values of 0.13, 0.24, and 0.3 μg/ml, respectively. It also inhibits HIV-1 replication in MT-2 T lymphoblastoid cells with an EC50 value of 2 μg/ml. 4,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 19.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF; ) and cytochalasin B (; IC50 = 1.49 μM). It decreases prostaglandin E2 (PGE2; ) production in LPS-stimulated U937 cells when used at concentrations of 5 and 10 μg/ml but increases it when used at 200 μg/ml and increases production of TNF-α at concentrations ranging from 5 to 200 μg/ml. It inhibits the synthesis of MCP3 in U937 cells. 4,5-DCQA (25 μM) inhibits melanogenesis by 84% and decreases the levels of proteins involved in melanin biosynthesis, including tyrosinase, TRP-1, DCT, and MITF in B16F1 murine melanocytes.Related product price
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