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ChemicalBook >> CAS DataBase List >> Itraconazole

Itraconazole

$6 - $1504.5
Product name: Itraconazole
CAS: 84625-61-6
MF: C35H38Cl2N8O4
MW: 705.63
EINECS:617-596-9
MDL Number:MFCD00870168
Synonyms:Oriconazole, R51211, Sporanox;4-[4-[4-[4-[[2-(2，4-Dichlomphenyl)-2-(1H-1，2，4-tfiazol-1- yl-methyl)-1,3-dioxolan-4-y1]methoxyl]phenyl]-1-piperazinyl]phenyl]-2，4-dihydro-2-(1-methylpropyl)-3H-1，2，4-triazol-3-one;Oricomzole;Oyiconazole;3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)- 1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-;Canditral;Sporamelt;4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(1-methylpropyl)-2,4-dihydro-1,2,4-triazol-3-one

Price49 Properties Safety Information Description

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Alfa Aesar
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Biorbyt Ltd
Cayman Chemical
Chem-Impex
ChemScene
CSNpharm
DC Chemicals
Medical Isotopes, Inc.
Sigma-Aldrich
TCI Chemical
Tocris
TRC
Usbiological

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y0001100
5MG
20mg
1mg
50
i7000000
25mg
50mg
100mg
200mg
250mg
500mg
1g
1mL
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10g
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ManufacturerAlfa Aesar
Product numberJ66390
Product descriptionItraconazole, 98%
Packaging1g
Price$91.8
Updated2024-03-01
Buy

ManufacturerAlfa Aesar
Product numberJ66390
Product descriptionItraconazole, 98%
Packaging5g
Price$180
Updated2024-03-01
Buy

ManufacturerAlfa Aesar
Product numberJ66390
Product descriptionItraconazole, 98%
Packaging25g
Price$795
Updated2024-03-01
Buy

ManufacturerAmbeed
Product numberA154189
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 98+%
Packaging1g
Price$10
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA154189
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 98+%
Packaging10g
Price$53
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA154189
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 98+%
Packaging25g
Price$105
Updated2021-12-16
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ManufacturerAmbeed
Product numberA154189
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 98+%
Packaging100g
Price$320
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberRDL0006888
Product descriptionITRACONAZOLE-D3 95.00%
Packaging5MG
Price$505.15
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB2104
Product descriptionItraconazole
Packaging1g
Price$250
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS036635
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%
Packaging100mg
Price$6
Updated2021-12-16
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ManufacturerArctom
Product numberAS036635
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%
Packaging250mg
Price$8
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS036635
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%
Packaging1g
Price$10
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS036635
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%
Packaging5g
Price$29
Updated2021-12-16
Buy

ManufacturerArctom
Product numberCFN60376
Product descriptionItraconazole ≥98%
Packaging20mg
Price$30
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS036635
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%
Packaging10g
Price$52
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS036635
Product description4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%
Packaging25g
Price$104
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Alfa Aesar	J66390	Itraconazole, 98%	1g	$91.8	2024-03-01	Buy
Alfa Aesar	J66390	Itraconazole, 98%	5g	$180	2024-03-01	Buy
Alfa Aesar	J66390	Itraconazole, 98%	25g	$795	2024-03-01	Buy
Ambeed	A154189	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 98+%	1g	$10	2021-12-16	Buy
Ambeed	A154189	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 98+%	10g	$53	2021-12-16	Buy
Ambeed	A154189	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 98+%	25g	$105	2021-12-16	Buy
Ambeed	A154189	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 98+%	100g	$320	2021-12-16	Buy
American Custom Chemicals Corporation	RDL0006888	ITRACONAZOLE-D3 95.00%	5MG	$505.15	2021-12-16	Buy
ApexBio Technology	B2104	Itraconazole	1g	$250	2021-12-16	Buy
Arctom	AS036635	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%	100mg	$6	2021-12-16	Buy
Arctom	AS036635	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%	250mg	$8	2021-12-16	Buy
Arctom	AS036635	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%	1g	$10	2021-12-16	Buy
Arctom	AS036635	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%	5g	$29	2021-12-16	Buy
Arctom	CFN60376	Itraconazole ≥98%	20mg	$30	2021-12-16	Buy
Arctom	AS036635	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%	10g	$52	2021-12-16	Buy
Arctom	AS036635	4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one ≥98%	25g	$104	2021-12-16	Buy

Next Last

Properties

Melting point :166°C
Boiling point :850.0±75.0 °C(Predicted)
alpha :-0.1～+0.1°(D/20℃)(c=10,CH2Cl2)
Density :1.27 g/cm3
Flash point :>110°(230°F)
storage temp. :2-8°C
solubility :chloroform: 50 mg/mL, clear, colorless
pka :3.7(at 25℃)
form :White powder
color :white
Water Solubility :Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol
Merck :14,5245
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :VHVPQPYKVGDNFY-UHFFFAOYSA-N
CAS DataBase Reference :84625-61-6(CAS DataBase Reference)

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The Hedgehog signaling pathway is critical for embryonic growth and patterning as well as stem cell and progenitor cell tissue homeostasis. Inappropriate Hedgehog activity has been linked to tumor formation. Itraconazole is a systemic antifungal agent with a distinct antagonist effect on Hedgehog signaling. With an IC50 value of 0.8 μM in vitro, itraconazole behaves as an inverse agonist downstream of Patched (Ptch), yet upstream of Smoothened (Smo) to disrupt Hedgehog signaling. Treatment with 100 mg/kg itraconazole twice per day has been shown to suppress the growth of medulloblastomas from a Ptch+/-p53-/- mouse allograft model in as few as five days.

More related product prices

1,4-Dioxane Selenium dioxide Dichlorodiphenylsilane 149-74-6 cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl methanesulphonate 155270-99-8 188116-07-6 IXABEPILONE trans-Itraconazole 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate edoxaban Imatinib 4-([4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-CARBAMIC ACID PHENYL ESTER 4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(2,3,4,4,4-pentadeuterio-3-hydroxybutan-2-yl)-1,2,4-triazol-3-one

Suppliers and manufacturers

Hebei Lingding Biotechnology Co., Ltd.

$500.00 /1KG
Itraconazole CAS:84625-61-6

Hebei Weibang Biotechnology Co., Ltd

$100.00 /25KG
Itraconazole CAS:84625-61-6

Hebei Mojin Biotechnology Co., Ltd

$10.00 /25KG
Itraconazol CAS:84625-61-6

Hebei Yanxi Chemical Co., Ltd.

$0.00 /1KG
Itraconazole CAS:84625-61-6

Wuhan Fortuna Chemical Co., Ltd

$0.00 /25Kg/Drum
Itraconazole CAS:84625-61-6

Hebei Weibang Biotechnology Co., Ltd

$0.00 /25KG
Itraconazole CAS:84625-61-6

Shandong Huisheng Import & Export Co., Ltd.

$0.00 /1KG
Itraconazole CAS:84625-61-6

Anhui Zhongda Biotechnology Co., Ltd

$0.00 /100g
Itraconazole CAS:84625-61-6

Anhui Zhongda Biotechnology Co., Ltd

$70.00/kg
Itraconazole CAS:84625-61-6

Anhui Ruihan Technology Co., Ltd

$30.00 /1kg
Itraconazole CAS:84625-61-6

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Itraconazole

Properties

Safety Information

Description

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