JC-1
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- $68 - $3900
- Product name: JC-1
- CAS: 3520-43-2
- MF: C25H27Cl4N4.I
- MW: 652.228
- EINECS:200-258-5
- MDL Number:MFCD00188475
- Synonyms:5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide;JC-1;JC-1,5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine iodide, 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolocarbocyanine iodide, CBIC2(3);JC-1 jodide;1h-benzimidazolium, 5,6-dichloro-2[3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2h-benzimidazol-2-ylidene)-1-propenyl]-1,3-diethyl-, Iodide;5,6-dichloro-2-[3-(5,6-dichloro-1,3-diethyl-2-benzimidazolinylidene)propenyl]-1,3-diethylbenzimidazolium Iodide;Benzimidazolium, 5,6-dichloro-2-[3-(5,6-dichloro-1,3diethyl-2-benzimidazolinylidene)propenyl]-1,3-diethyl-, Iodide;Benzimidazolocarbocyanine Iodide, 5,50,6,60-tetrachloro-1,10,3,30-tetraethyl-
20 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 002
- 001
- 003
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 50mg
- 200mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3568-M005
- Product descriptionJC-1 ≥98%(NMR)
- Packaging5mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3006BB
- Product description1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanineiodide
- Packaging1mg
- Price$174
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3516
- Product descriptionJC-1
- Packaging1mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3516
- Product descriptionJC-1
- Packaging200mg
- Price$2299
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15003
- Product descriptionJC-1 ≥90%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15003
- Product descriptionJC-1 ≥90%
- Packaging5mg
- Price$302
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15003
- Product descriptionJC-1 ≥90%
- Packaging10mg
- Price$535
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number41986
- Product descriptionJC-1,≥97%(HPLC),suitableforHematology&Histology ≥97%(HPLC)
- Packaging5MG
- Price$542.8
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1148
- Product descriptionJC-1 99.00%
- Packaging2mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1148
- Product descriptionJC-1 99.00%
- Packaging5mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1148
- Product descriptionJC-1 99.00%
- Packaging10mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1148
- Product descriptionJC-1 99.00%
- Packaging50mg
- Price$1280
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11137791
- Product descriptionJC-1 97%
- Packaging5mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11137791
- Product descriptionJC-1 97%
- Packaging10mg
- Price$265
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product number025867
- Product descriptionJC-1
- Packaging001
- Price$950
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product number025867
- Product descriptionJC-1
- Packaging002
- Price$1900
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3568-M005 | JC-1 ≥98%(NMR) | 5mg | $180 | 2021-12-16 | Buy |
| AK Scientific | 3006BB | 1,1',3,3'-Tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanineiodide | 1mg | $174 | 2021-12-16 | Buy |
| ApexBio Technology | A3516 | JC-1 | 1mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | A3516 | JC-1 | 200mg | $2299 | 2021-12-16 | Buy |
| Cayman Chemical | 15003 | JC-1 ≥90% | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 15003 | JC-1 ≥90% | 5mg | $302 | 2024-03-01 | Buy |
| Cayman Chemical | 15003 | JC-1 ≥90% | 10mg | $535 | 2024-03-01 | Buy |
| Chem-Impex | 41986 | JC-1,≥97%(HPLC),suitableforHematology&Histology ≥97%(HPLC) | 5MG | $542.8 | 2021-12-16 | Buy |
| ChemScene | CS-1148 | JC-1 99.00% | 2mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-1148 | JC-1 99.00% | 5mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-1148 | JC-1 99.00% | 10mg | $300 | 2021-12-16 | Buy |
| ChemScene | CS-1148 | JC-1 99.00% | 50mg | $1280 | 2021-12-16 | Buy |
| Crysdot | CD11137791 | JC-1 97% | 5mg | $160 | 2021-12-16 | Buy |
| Crysdot | CD11137791 | JC-1 97% | 10mg | $265 | 2021-12-16 | Buy |
| DC Chemicals | 025867 | JC-1 | 001 | $950 | 2021-12-16 | Buy |
| DC Chemicals | 025867 | JC-1 | 002 | $1900 | 2021-12-16 | Buy |
Properties
Melting point :275–278 ℃
storage temp. :room temp
solubility :Soluble in methanol, N,N-dimethyl formamide, dimethyl sulfoxide
form :crystals
color :Deep red
λmax :514nm
Stability :Store as supplied desiccated at -20°C for up to 2 years from the date of purchase. Solutions in DMSO or distilled water may be stored at 4°C for up to 1 year. DO NOT FREEZE/THAW SOLUTIONS. Sterilize solutions only by filtration, not by autoclaving
Biological Applications :Detectingmitochondrialmembrane potential,ABCB1,ABCC1,and ABCG2 transporters inhibitors,nucleic acid hybridization,prostate cancer; treating cellular death,Alzheimer’s disease; apoptosis assay; cytotoxicity assay; hematotoxicity
Major Application :Langmuir-Blodgett films; lasing systems; nonlinear optical materials; photographic materials1,
InChIKey :FYNNIUVBDKICAX-UHFFFAOYSA-M
storage temp. :room temp
solubility :Soluble in methanol, N,N-dimethyl formamide, dimethyl sulfoxide
form :crystals
color :Deep red
λmax :514nm
Stability :Store as supplied desiccated at -20°C for up to 2 years from the date of purchase. Solutions in DMSO or distilled water may be stored at 4°C for up to 1 year. DO NOT FREEZE/THAW SOLUTIONS. Sterilize solutions only by filtration, not by autoclaving
Biological Applications :Detectingmitochondrialmembrane potential,ABCB1,ABCC1,and ABCG2 transporters inhibitors,nucleic acid hybridization,prostate cancer; treating cellular death,Alzheimer’s disease; apoptosis assay; cytotoxicity assay; hematotoxicity
Major Application :Langmuir-Blodgett films; lasing systems; nonlinear optical materials; photographic materials1,
InChIKey :FYNNIUVBDKICAX-UHFFFAOYSA-M
Safety Information
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Description
JC-1 is a membrane-permeable cationic dye that is used to study mitochondrial integrity in the context of cellular apoptosis. It selectively enters mitochondria and changes fluorescence characteristics with alteration in mitochondrial transmembrane potential (ΔΨm). In healthy cells with a high mitochondrial ΔΨm, JC-1 forms complexes known as J-aggregates, which fluoresce red/orange and may be detected using FL2 settings by flow cytometry. A drop in ΔΨm, a very early event in apoptosis, results in JC-1 monomers, which fluoresce green (FL1 settings on flow cytometers). JC-1 may also be used with fluorescent microscopes or plate readers, using excitation at 520-570 nm and emission at 570-610 nm for J-aggregates and excitation at 485 nm and emission at 535 nm for monomers.Related product price
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