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ChemicalBook >> CAS DataBase List >> KT5823

KT5823

KT5823 price.
  • $37 - $460
  • Product name: KT5823
  • CAS: 126643-37-6
  • MF: C29H25N3O5
  • MW: 495.53
  • EINECS:603-150-0
  • MDL Number:MFCD09878278
  • Synonyms:PROTEIN KINASE INHIBITOR KT 5823;9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, (9S,10R,12R)-;(9S, 10R, 12R)-2,3,9,10,11,12-HEXAHYDRO-10-METHOXY-2,9-DIMETHYL-1-OXO-9,12-EPOXY-1H-DIINDOLO[1,2,3-FG:3',2',1'-KL]PYRROLO[3,4-I][1,6]BENZODIAZOCINE-10-CARBOXYLIC ACID, METHYL ESTER;(9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, methyl ester;(9R)-2,3,9,10,11,12-Hexahydro-10β-methoxy-2,9-dimethyl-1-oxo-9α,12α-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester;9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-I)(1,6)benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, (9R-(9alpha,10beta,12alpha))-;9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-I)(1,6)benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, (9R,10R,12R)-;9-Methoxy-9-methoxycarbonyl-8-methyl-2,3,9,10-tetrahydro-8,11-epxoy-1H,8H,11H-2,7B-11A-triazadibenzo(A,G)cycloocta(cde)-trinden-1-one
15 prices
Selected condition:
Brand
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 25μg
  • 50ug
  • 50μg
  • 100ug
  • 100μg
  • 250ug
  • 500μg
  • 100U
  • ManufacturerApexBio Technology
  • Product numberB6673
  • Product descriptionKT5823
  • Packaging50ug
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6673
  • Product descriptionKT5823
  • Packaging100ug
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6673
  • Product descriptionKT5823
  • Packaging250ug
  • Price$311
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010965
  • Product descriptionKT 5823 ≥95%
  • Packaging25μg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010965
  • Product descriptionKT 5823 ≥95%
  • Packaging50μg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010965
  • Product descriptionKT 5823 ≥95%
  • Packaging100μg
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010965
  • Product descriptionKT 5823
  • Packaging500μg
  • Price$424
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014218
  • Product descriptionKT5823 ≥99.0%
  • Packaging100ug
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberK1388
  • Product descriptionKT 5823 ≥85% (HPLC), lyophilized powder
  • Packaging100μg
  • Price$219
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number420321
  • Product descriptionKT5823 - CAS 126643-37-6 - Calbiochem Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).
  • Packaging50μg
  • Price$159
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number420321
  • Product descriptionKT5823 - CAS 126643-37-6 - Calbiochem Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).
  • Packaging100μg
  • Price$259
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number1289
  • Product descriptionKT5823 ≥98%(HPLC)
  • Packaging100U
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberK660350
  • Product descriptionKT5823
  • Packaging100μg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number167898
  • Product descriptionKT5823
  • Packaging50ug
  • Price$319
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255612
  • Product descriptionKT 5823
  • Packaging100ug
  • Price$460
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B6673 KT5823 50ug $74 2021-12-16 Buy
ApexBio Technology B6673 KT5823 100ug $140 2021-12-16 Buy
ApexBio Technology B6673 KT5823 250ug $311 2021-12-16 Buy
Cayman Chemical 10010965 KT 5823 ≥95% 25μg $37 2024-03-01 Buy
Cayman Chemical 10010965 KT 5823 ≥95% 50μg $68 2024-03-01 Buy
Cayman Chemical 10010965 KT 5823 ≥95% 100μg $108 2024-03-01 Buy
Cayman Chemical 10010965 KT 5823 500μg $424 2024-03-01 Buy
ChemScene CS-0014218 KT5823 ≥99.0% 100ug $380 2021-12-16 Buy
Sigma-Aldrich K1388 KT 5823 ≥85% (HPLC), lyophilized powder 100μg $219 2024-03-01 Buy
Sigma-Aldrich 420321 KT5823 - CAS 126643-37-6 - Calbiochem Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM). 50μg $159 2024-03-01 Buy
Sigma-Aldrich 420321 KT5823 - CAS 126643-37-6 - Calbiochem Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM). 100μg $259 2024-03-01 Buy
Tocris 1289 KT5823 ≥98%(HPLC) 100U $212 2021-12-16 Buy
TRC K660350 KT5823 100μg $105 2021-12-16 Buy
Usbiological 167898 KT5823 50ug $319 2021-12-16 Buy
Usbiological 255612 KT 5823 100ug $460 2021-12-16 Buy

Properties

Boiling point :629.2±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :ethyl acetate: 5 mg/mL
form :lyophilized powder
pka :-1.01±0.60(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

KT5823 (126643-37-6) is a selective protein kinase G inhibitor (K>i =0.23, 4 and >10 μM for PKG, PKC and PKA respectively.1?Arrests human skin fibroblast cell cycle after the G0/G1 boundary.2 KT5823 abolishes the cGMP-induced relaxation in smooth muscle cells (IC50=60 nM).3?Cell permeable.

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