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ChemicalBook >> CAS DataBase List >> LASOFOXIFENE HCL

LASOFOXIFENE HCL

LASOFOXIFENE HCL price.
  • $40 - $1504.5
  • Product name: LASOFOXIFENE HCL
  • CAS: 190791-29-8
  • MF: C32H37NO8
  • MW: 563.65
  • EINECS:
  • MDL Number:MFCD13185249
  • Synonyms:2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-, (5R,6S)-, (2S,3S)-2,3-dihydroxybutanedioate (1:1) (salt);2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-, (5R-cis)-, (S-(R*,R*))-2,3-dihydroxybutanedioate (1:1) (salt);Cb 336156eb;Unii-85X09V2gso;(5R,6S)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol (2S,3S)-2,3-dihydroxybutanedioate (1:1);(-)-cis-6-Phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol tartrate;(5R,6S)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol tartrate;CP-336,156 tartrate
27 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0943BB
  • Product descriptionLasofoxifene Tartrate
  • Packaging5mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0943BB
  • Product descriptionLasofoxifene Tartrate
  • Packaging1g
  • Price$1473
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA367118
  • Product descriptionLasofoxifene Tartrate 98+%
  • Packaging5mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA367118
  • Product descriptionLasofoxifene Tartrate 98+%
  • Packaging10mg
  • Price$52
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA367118
  • Product descriptionLasofoxifene Tartrate 98+%
  • Packaging50mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5637
  • Product descriptionLasofoxifene Tartrate
  • Packaging10mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5637
  • Product descriptionLasofoxifene Tartrate
  • Packaging25mg
  • Price$244
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5637
  • Product descriptionLasofoxifene Tartrate
  • Packaging50mg
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS535458
  • Product descriptionLasofoxifene Tartrate ≥98%
  • Packaging100mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS535458
  • Product descriptionLasofoxifene Tartrate ≥98%
  • Packaging250mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS535458
  • Product descriptionLasofoxifene Tartrate ≥98%
  • Packaging1g
  • Price$823
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134806
  • Product descriptionLasofoxifene tartrate >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134806
  • Product descriptionLasofoxifene tartrate >99%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134806
  • Product descriptionLasofoxifene tartrate >99%
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17646
  • Product descriptionLasofoxifene (tartrate) ≥98%
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17646
  • Product descriptionLasofoxifene (tartrate) ≥98%
  • Packaging10mg
  • Price$92
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0943BB Lasofoxifene Tartrate 5mg $118 2021-12-16 Buy
AK Scientific 0943BB Lasofoxifene Tartrate 1g $1473 2021-12-16 Buy
Ambeed A367118 Lasofoxifene Tartrate 98+% 5mg $40 2021-12-16 Buy
Ambeed A367118 Lasofoxifene Tartrate 98+% 10mg $52 2021-12-16 Buy
Ambeed A367118 Lasofoxifene Tartrate 98+% 50mg $88 2021-12-16 Buy
ApexBio Technology C5637 Lasofoxifene Tartrate 10mg $103 2021-12-16 Buy
ApexBio Technology C5637 Lasofoxifene Tartrate 25mg $244 2021-12-16 Buy
ApexBio Technology C5637 Lasofoxifene Tartrate 50mg $432 2021-12-16 Buy
Arctom AS535458 Lasofoxifene Tartrate ≥98% 100mg $220 2021-12-16 Buy
Arctom AS535458 Lasofoxifene Tartrate ≥98% 250mg $330 2021-12-16 Buy
Arctom AS535458 Lasofoxifene Tartrate ≥98% 1g $823 2021-12-16 Buy
Biorbyt Ltd orb134806 Lasofoxifene tartrate >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb134806 Lasofoxifene tartrate >99% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb134806 Lasofoxifene tartrate >99% 1g $1504.5 2021-12-16 Buy
Cayman Chemical 17646 Lasofoxifene (tartrate) ≥98% 5mg $49 2024-03-01 Buy
Cayman Chemical 17646 Lasofoxifene (tartrate) ≥98% 10mg $92 2024-03-01 Buy

Properties

Melting point :185 °C(dec.)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Lasofoxifene is a third-generation, non-steroidal selective estrogen receptor modulator (SERM). It selectively binds to human ERα with an IC50 value of 1.5 nM and inhibits bone loss in ovariectomized rats. In clinical studies of postmenopausal osteoporosis, 0.5 mg/day lasofoxifene was associated with reduced risks of nonvertebral and vertebral fractures, ER-positive breast cancer, coronary heart disease, and stroke but an increased risk of venous thromboembolic events. Lasofoxifene has also been shown to act as an inverse agonist at the CB2 cannabinoid receptor, indicating its potential to be repurposed as a therapeutic for indications wherein CB2 is a target.

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