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ChemicalBook >> CAS DataBase List >> MAFP

MAFP

MAFP price.
  • $34 - $739.78
  • Product name: MAFP
  • CAS: 188404-10-6
  • MF: C21H36FO2P
  • MW: 370.48
  • EINECS:201-185-2
  • MDL Number:MFCD03095722
  • Synonyms:5Z,8Z,11Z,14Z-EICOSATETRAENYL-PHOSPHONOFLUORIDIC ACID, METHYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENYL-METHYL ESTER PHOSPHONOFLUORIDIC ACID;MAFP;MAPF;METHYL-5Z,8Z,11Z,14Z-EICOSATETRAENYL ESTER PHOSPHONOFLUORIDIC ACID METHYL ACETATE;METHYL ARACHIDONYL FLUOROPHOSPHONATE;METHYLPHOSPHONOFLUORIDIC ACID 5,8,11,14-EICOSATETRAENYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenylmethylester
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • CSNpharm
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10MG
  • 25mg
  • ManufacturerAK Scientific
  • Product number1842AH
  • Product descriptionMAFP
  • Packaging5mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67139
  • Product descriptionMethyl arachidonyl fluorophosphonate, 98%
  • Packaging5mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA148645
  • Product description(all-Z)-5,8,11,14-EicosatetraenylphosphonofluoridicAcidMethylEster 95%
  • Packaging1mg
  • Price$107
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA148645
  • Product description(all-Z)-5,8,11,14-EicosatetraenylphosphonofluoridicAcidMethylEster 95%
  • Packaging5mg
  • Price$335
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004954
  • Product descriptionMETHYL ARACHIDONYL FLUOROPHOSPHONATE 95.00%
  • Packaging1MG
  • Price$569.99
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004954
  • Product descriptionMETHYL ARACHIDONYL FLUOROPHOSPHONATE 95.00%
  • Packaging5MG
  • Price$686.07
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004954
  • Product descriptionMETHYL ARACHIDONYL FLUOROPHOSPHONATE 95.00%
  • Packaging10MG
  • Price$739.78
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6732
  • Product descriptionMAFP
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number70660
  • Product descriptionMethyl Arachidonyl Fluorophosphonate ≥98%
  • Packaging1mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70660
  • Product descriptionMethyl Arachidonyl Fluorophosphonate ≥98%
  • Packaging5mg
  • Price$119
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70660
  • Product descriptionMethyl Arachidonyl Fluorophosphonate ≥98%
  • Packaging10mg
  • Price$220
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70660
  • Product descriptionMethyl Arachidonyl Fluorophosphonate ≥98%
  • Packaging25mg
  • Price$465
  • Updated2024-03-01
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN25339
  • Product descriptionMAFP
  • Packaging1mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN25339
  • Product descriptionMAFP
  • Packaging5mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberM2939
  • Product descriptionMethyl arachidonyl fluorophosphonate ≥98%, methyl acetate solution (10 mg/mL)
  • Packaging5MG
  • Price$241
  • Updated2023-06-20
  • Buy
  • ManufacturerTRC
  • Product numberE477895
  • Product description(all-Z)-5,8,11,14-EicosatetraenylphosphonofluoridicAcidMethylEster
  • Packaging5mg
  • Price$165
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1842AH MAFP 5mg $226 2021-12-16 Buy
Alfa Aesar J67139 Methyl arachidonyl fluorophosphonate, 98% 5mg $173 2021-12-16 Buy
Ambeed A148645 (all-Z)-5,8,11,14-EicosatetraenylphosphonofluoridicAcidMethylEster 95% 1mg $107 2021-12-16 Buy
Ambeed A148645 (all-Z)-5,8,11,14-EicosatetraenylphosphonofluoridicAcidMethylEster 95% 5mg $335 2021-12-16 Buy
American Custom Chemicals Corporation INB0004954 METHYL ARACHIDONYL FLUOROPHOSPHONATE 95.00% 1MG $569.99 2021-12-16 Buy
American Custom Chemicals Corporation INB0004954 METHYL ARACHIDONYL FLUOROPHOSPHONATE 95.00% 5MG $686.07 2021-12-16 Buy
American Custom Chemicals Corporation INB0004954 METHYL ARACHIDONYL FLUOROPHOSPHONATE 95.00% 10MG $739.78 2021-12-16 Buy
ApexBio Technology B6732 MAFP 5mg $130 2021-12-16 Buy
Cayman Chemical 70660 Methyl Arachidonyl Fluorophosphonate ≥98% 1mg $34 2024-03-01 Buy
Cayman Chemical 70660 Methyl Arachidonyl Fluorophosphonate ≥98% 5mg $119 2024-03-01 Buy
Cayman Chemical 70660 Methyl Arachidonyl Fluorophosphonate ≥98% 10mg $220 2024-03-01 Buy
Cayman Chemical 70660 Methyl Arachidonyl Fluorophosphonate ≥98% 25mg $465 2024-03-01 Buy
CSNpharm CSN25339 MAFP 1mg $80 2021-12-16 Buy
CSNpharm CSN25339 MAFP 5mg $250 2021-12-16 Buy
Sigma-Aldrich M2939 Methyl arachidonyl fluorophosphonate ≥98%, methyl acetate solution (10 mg/mL) 5MG $241 2023-06-20 Buy
TRC E477895 (all-Z)-5,8,11,14-EicosatetraenylphosphonofluoridicAcidMethylEster 5mg $165 2021-12-16 Buy

Properties

Boiling point :455.3±34.0 °C(Predicted)
Density :0.960±0.06 g/cm3(Predicted)
RTECS :TA8108000
Flash point :-16 °C
storage temp. :-70°C
solubility :DMF: 3 mg/ml; DMSO: 3 mg/ml; Ethanol: 3.5 mg/ml; Ethanol:PBS (pH 7.2) 1:1: .5 mg/ml; PBS (7.2): <1 mg/ml (colloidal suspension
form :methyl acetate solution
color :Light yellow to yellow
Sensitive :Air Sensitive

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Methyl arachidonyl fluorophosphonate (MAFP) is a selective, active-site directed, irreversible inhibitor of cPLA2 and iPLA2. It inhibits A23187-induced arachidonic acid release from human platelets with an IC50 value of 0.6 μM. The IC50 value for inhibition of iPLA2 from P388D1 cells is 0.5 μM. MAFP is a potent inhibitor of fatty acid amide hydrolase, exhibiting an IC50 value of 2.5 nM. MAFP also binds to the CB1 receptor in rat brain membrane preparations. The IC50 values for MAFP and arachidonyl ethanolamide in this assay are 20 and 40 nM, respectively.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
Aladdin Scientific J & K SCIENTIFIC LTD. 3B Pharmachem (Wuhan) International Co.,Ltd. Shanghai TaoSu Biochemical Technology Co., Ltd. Sigma-Aldrich EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd. Beijing Solarbio Science & Tecnology Co., Ltd.