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ChemicalBook >> CAS DataBase List >> MS023

MS023

MS023 price.
  • $41 - $2517
  • Product name: MS023
  • CAS: 1831110-54-3
  • MF: C17H25N3O
  • MW: 287.4
  • EINECS:
  • MDL Number:MFCD29924734
  • Synonyms:MS023;N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine;(2-aminoethyl)(methyl)({4-[4-(propan-2-yloxy)phenyl]-1H-pyrrol-3-yl}methyl)amine;CS-2284;MS023 (MS-023;1,2-Ethanediamine, N1-methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-;Inhibitor,MS 023,MS-023,MS023,inhibit,Histone Methyltransferase
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  • AK Scientific
  • Ambeed
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  • ManufacturerAK Scientific
  • Product number6212EC
  • Product descriptionMS023
  • Packaging5mg
  • Price$151
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6212EC
  • Product descriptionMS023
  • Packaging50mg
  • Price$438
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6212EC
  • Product descriptionMS023
  • Packaging250mg
  • Price$1042
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6212EC
  • Product descriptionMS023
  • Packaging1g
  • Price$2517
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA604225
  • Product descriptionMS023 98+%
  • Packaging1g
  • Price$1820
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA604225
  • Product descriptionMS023 98+%
  • Packaging250mg
  • Price$728
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA604225
  • Product descriptionMS023 98+%
  • Packaging100mg
  • Price$364
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA604225
  • Product descriptionMS023 98+%
  • Packaging50mg
  • Price$280
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA604225
  • Product descriptionMS023 98+%
  • Packaging25mg
  • Price$211
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA604225
  • Product descriptionMS023 98+%
  • Packaging10mg
  • Price$102
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA604225
  • Product descriptionMS023 98+%
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA604225
  • Product descriptionMS023 98+%
  • Packaging2mg
  • Price$41
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB6183
  • Product descriptionMS023
  • Packaging5mg
  • Price$89
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB6183
  • Product descriptionMS023
  • Packaging25mg
  • Price$313
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS610935
  • Product descriptionMS023 ≥98%
  • Packaging2mg
  • Price$41
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS610935
  • Product descriptionMS023 ≥98%
  • Packaging5mg
  • Price$67
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6212EC MS023 5mg $151 2021-12-16 Buy
AK Scientific 6212EC MS023 50mg $438 2021-12-16 Buy
AK Scientific 6212EC MS023 250mg $1042 2021-12-16 Buy
AK Scientific 6212EC MS023 1g $2517 2021-12-16 Buy
Ambeed A604225 MS023 98+% 1g $1820 2021-12-16 Buy
Ambeed A604225 MS023 98+% 250mg $728 2021-12-16 Buy
Ambeed A604225 MS023 98+% 100mg $364 2021-12-16 Buy
Ambeed A604225 MS023 98+% 50mg $280 2021-12-16 Buy
Ambeed A604225 MS023 98+% 25mg $211 2021-12-16 Buy
Ambeed A604225 MS023 98+% 10mg $102 2021-12-16 Buy
Ambeed A604225 MS023 98+% 5mg $68 2021-12-16 Buy
Ambeed A604225 MS023 98+% 2mg $41 2021-12-16 Buy
ApexBio Technology B6183 MS023 5mg $89 2021-12-16 Buy
ApexBio Technology B6183 MS023 25mg $313 2021-12-16 Buy
Arctom AS610935 MS023 ≥98% 2mg $41 2021-12-16 Buy
Arctom AS610935 MS023 ≥98% 5mg $67 2021-12-16 Buy

Properties

Boiling point :437.8±45.0 °C(Predicted)
Density :1.075±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :≥28.7 mg/mL in DMSO; ≥13.7 mg/mL in EtOH; ≥23.3 mg/mL in H2O
form :powder
pka :17.44±0.50(Predicted)
color :white to light brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

MS023 is a potent, selective, and cell-active inhibitor of human type PRMTs (protein arginine methyltransferase), which is involved in many biological processes. Overexpression of PRMTs is related to some cancers. Therefore, MS023 is a useful chemical tools for testing biological and therapeutic hypotheses. MS023 displayed high potency for type I PRMTs including PRMT1, -3, -4, -6, and -8 but was completely inactive against type II and type III PRMTs, protein lysine methyltransferases and DNA methyltransferases. MS023 potently decreased cellular levels of histone arginine asymmetric dimethylation. It also reduced global levels of arginine asymmetric dimethylation and concurrently increased levels of arginine monomethylation and symmetric dimethylation in cells.

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