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ChemicalBook >> CAS DataBase List >> NADOLOL

NADOLOL

NADOLOL price.
  • $79 - $3670
  • Product name: NADOLOL
  • CAS: 42200-33-9
  • MF: C17H27NO4
  • MW: 309.4
  • EINECS:255-706-3
  • MDL Number:MFCD00079476
  • Synonyms:1-(tert-butylamino)-3-((5,6,7,8-tetrahydro-cis-6,7-dihydroxy-1-naphthyl)oxy) ;1-(tert-bytylamino)-3-((5,6,7,8-tetrahydro-cis-6,7-dihydroxy-1-naphthyl)oxy)-2 ;2,3-cis-1,2,3,4-tetrahydro-5-((2-hydroxy-3-tert-butylamino)propoxy)-2,3-naph ;2,3-cis-1,2,3,4-Tetrahydro-5-((2-hydroxy-3-tert-butylamino)propoxy)-2,3-naphthalenediol;2,3-cis-1,2,3,4-tetrahydro-5-(2-hydroxy-3-(tert-butylamino)propoxy)-2,3-naphth ;2,3-diol ;2,3-Naphthalenediol, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,2,3,4-tetrahydro-;2,3-Naphthalenediol, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,2,3,4-tetrahydro-, cis-
Price22 Properties Safety Information Description
22 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AHH
  • American Custom Chemicals Corporation
  • Chemenu
  • ChemScene
  • Crysdot
  • Matrix Scientific
  • Sigma-Aldrich
  • TRC
Package
  • 1MG
  • 2.5MG
  • 10MG
  • 25MG
  • 100mg
  • 200mg
  • 250mg
  • 400MG
  • 500mg
  • 1g
  • 5G
  • y0000146
  • 10g
  • 25g
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-N0141-G005
  • Product descriptionNadolol ≥98%(GC)
  • Packaging5G
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-56366
  • Product descriptionNadolol 98%
  • Packaging25g
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBAR0001587
  • Product descriptionNADOLOL-D9 95.00%
  • Packaging1MG
  • Price$779.63
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBAR0001587
  • Product descriptionNADOLOL-D9 95.00%
  • Packaging2.5MG
  • Price$1235
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBAR0001587
  • Product descriptionNADOLOL-D9 95.00%
  • Packaging10MG
  • Price$2194.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBAR0001587
  • Product descriptionNADOLOL-D9 95.00%
  • Packaging25MG
  • Price$3670
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM139860
  • Product description(2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95%
  • Packaging5g
  • Price$448
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM139860
  • Product description(2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95%
  • Packaging10g
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012452
  • Product descriptionNadolol 98.58%
  • Packaging100mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012452
  • Product descriptionNadolol 98.58%
  • Packaging250mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012452
  • Product descriptionNadolol 98.58%
  • Packaging500mg
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12072897
  • Product description(2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+%
  • Packaging5g
  • Price$479
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12072897
  • Product description(2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+%
  • Packaging10g
  • Price$749
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number099589
  • Product description(2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+%
  • Packaging10g
  • Price$788
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number099589
  • Product description(2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+%
  • Packaging5g
  • Price$504
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number099589
  • Product description(2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+%
  • Packaging1g
  • Price$189
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-N0141-G005 Nadolol ≥98%(GC) 5G $212 2021-12-16 Buy
AHH MT-56366 Nadolol 98% 25g $250 2021-12-16 Buy
American Custom Chemicals Corporation BAR0001587 NADOLOL-D9 95.00% 1MG $779.63 2021-12-16 Buy
American Custom Chemicals Corporation BAR0001587 NADOLOL-D9 95.00% 2.5MG $1235 2021-12-16 Buy
American Custom Chemicals Corporation BAR0001587 NADOLOL-D9 95.00% 10MG $2194.5 2021-12-16 Buy
American Custom Chemicals Corporation BAR0001587 NADOLOL-D9 95.00% 25MG $3670 2021-12-16 Buy
Chemenu CM139860 (2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95% 5g $448 2021-12-16 Buy
Chemenu CM139860 (2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95% 10g $700 2021-12-16 Buy
ChemScene CS-0012452 Nadolol 98.58% 100mg $210 2021-12-16 Buy
ChemScene CS-0012452 Nadolol 98.58% 250mg $400 2021-12-16 Buy
ChemScene CS-0012452 Nadolol 98.58% 500mg $680 2021-12-16 Buy
Crysdot CD12072897 (2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+% 5g $479 2021-12-16 Buy
Crysdot CD12072897 (2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+% 10g $749 2021-12-16 Buy
Matrix Scientific 099589 (2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+% 10g $788 2021-12-16 Buy
Matrix Scientific 099589 (2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+% 5g $504 2021-12-16 Buy
Matrix Scientific 099589 (2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 95+% 1g $189 2021-12-16 Buy
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Properties

Melting point :125-130°C
Boiling point :449.67°C (rough estimate)
Density :1.0449 (rough estimate)
refractive index :1.5420 (estimate)
storage temp. :Refrigerator
solubility :Slightly soluble in water, freely soluble in ethanol (96 per cent), practically insoluble in acetone.
form :Solid
pka :9.67(at 25℃)
color :White to Off-White
Water Solubility :8.30g/L(25 ºC)
BCS Class :3
EPA Substance Registry System :2,3-Naphthalenediol, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,2,3,4-tetrahydro- (42200-33-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Nadolol is a polar and hydrophilic, non-selective β blocker, which displays activity against β-1 and β-2 receptors. It is known that Nadolol inhibits the release of catecholamines from the adrenal glands. Studies involving murine models of asthma suggest that Nadolol at higher concentrations decreases airway resistance response to the muscarinic agonist methacholine. At lower concentrations, Nadolol has the opposite effect. Research indicates that this is due to the fact that Nadolol at higher amounts decreases the degradation of the β-2 adrenergic receptor and increase production of the receptor. This receptor inhibition is due to forskolin- stimulated phosphorylation of the β-2 adrenergic receptor at Ser 262, when applied for 5 minutes. Interestingly, phosphorylation of the receptor is reduced upon application consisting of longer time periods.

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