Neoandrographolide
|
- $35 - $2395.3
- Product name: Neoandrographolide
- CAS: 27215-14-1
- MF: C26H40O8
- MW: 480.59
- EINECS:
- MDL Number:MFCD07779130
- Synonyms:3-[2-[(4as,5r,8as)-5,8a-dimethyl-2-methylidene-5-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1h-naphthalen-1-yl]ethyl]-5h-furan-2-one;ANDROGRAPHOLIDE, NEO-;NEOANDROGRAPHOLIDE;2(5H)-Furanone, 3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-;3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-Glucopyranosyloxy)methyl]-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,8a-dimethyl-2-methylenenaphthalene-1-yl]ethyl]-2(5H)-furanone;3-[2-[(1R,4aβ)-5α-[(β-D-Glucopyranosyloxy)methyl]decahydro-5,8aα-dimethyl-2-methylenenaphthalen-1α-yl]ethyl]furan-2(5H)-one;4-[2-[(4aS,5R,8aS)-5,8a-dimethyl-2-methylene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxymethyl]decalin-1-yl]ethyl]-2H-furan-5-one;4-[2-[(4aS,5R,8aS)-5,8a-dimethyl-2-methylidene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl]-2H-furan-5-one
40 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- DC Chemicals
- JR MediChem
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1MG
- 2mg
- 5mg
- 10mg
- 20mg
- 25mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number8182AH
- Product descriptionNeoandrographolide
- Packaging5mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8182AH
- Product descriptionNeoandrographolide
- Packaging10mg
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8182AH
- Product descriptionNeoandrographolide
- Packaging25mg
- Price$334
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA240618
- Product descriptionNeoandrographolide 98+%
- Packaging5mg
- Price$81
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA240618
- Product descriptionNeoandrographolide 98+%
- Packaging10mg
- Price$118
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0000574
- Product descriptionNEOANDROGRA-PHOLIDE 95.00%
- Packaging1MG
- Price$148.05
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0000574
- Product descriptionNEOANDROGRA-PHOLIDE 95.00%
- Packaging5MG
- Price$502.6
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging1mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging2mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging5mg
- Price$64
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN97766
- Product descriptionNeoandrographolide ≥98%
- Packaging20mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY009415
- Product description3-[2-[(1R,4aS,5R,8aS)-5-[(beta-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone
- Packaging10mg
- Price$171.82
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging25mg
- Price$221
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1813
- Product descriptionNeoandrographolide
- Packaging10mg
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594140
- Product descriptionNeoandrographolide
- Packaging20mg
- Price$375.7
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8182AH | Neoandrographolide | 5mg | $134 | 2021-12-16 | Buy |
| AK Scientific | 8182AH | Neoandrographolide | 10mg | $178 | 2021-12-16 | Buy |
| AK Scientific | 8182AH | Neoandrographolide | 25mg | $334 | 2021-12-16 | Buy |
| Ambeed | A240618 | Neoandrographolide 98+% | 5mg | $81 | 2021-12-16 | Buy |
| Ambeed | A240618 | Neoandrographolide 98+% | 10mg | $118 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0000574 | NEOANDROGRA-PHOLIDE 95.00% | 1MG | $148.05 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0000574 | NEOANDROGRA-PHOLIDE 95.00% | 5MG | $502.6 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 1mg | $35 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 2mg | $51 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 5mg | $64 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 10mg | $99 | 2021-12-16 | Buy |
| Arctom | CFN97766 | Neoandrographolide ≥98% | 20mg | $128 | 2021-12-16 | Buy |
| Arctom | SY009415 | 3-[2-[(1R,4aS,5R,8aS)-5-[(beta-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone | 10mg | $171.82 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 25mg | $221 | 2021-12-16 | Buy |
| AvaChem | 1813 | Neoandrographolide | 10mg | $239 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594140 | Neoandrographolide | 20mg | $375.7 | 2021-12-16 | Buy |
Properties
Melting point :167～168℃
Boiling point :668.1±55.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.93±0.70(Predicted)
form :Solid
color :White
Boiling point :668.1±55.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.93±0.70(Predicted)
form :Solid
color :White
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Neoandrographolide is one of the principle diterpenoids isolated from A. paniculata, a well-recognized medicinal plant in Asia. Extracts from A. paniculata have been reported to exert a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, anti-viral, anti-bacterial, anti-diabetic, anti-oxidative stress, antipyretic, anti-edematogenic, and anti-nociceptive activities. Neoandrographolide has been shown to inhibit LPS-induced nitric oxide production in inflammatory macrophages after oral administration to mice (25 mg/kg) or by direct addition to cultured macrophages (IC50 = 35.5 μM). At 25 μM, it can reduce VEGF-induced proliferation of human umbilical vein endothelial cells. Neoandrographolide also inhibits the pro-protein convertase furin with an IC50 value of 53.5 μM.Related product price
- Andrographolide
$10-640 - N,N-Dimethylformamide
$11.2-12200 - Dimethyl ether
$75-649
Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Hubei Jusheng Technology Co.,Ltd.
BOC Sciences
Chongqing Chemdad Co., Ltd
Neostar United (Changzhou) Industrial Co., Ltd.
