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ChemicalBook >> CAS DataBase List >> OG-L002

OG-L002

OG-L002 price.
  • $36 - $2839
  • Product name: OG-L002
  • CAS: 1357302-64-7
  • MF: C15H15NO
  • MW: 225.29
  • EINECS:
  • MDL Number:MFCD27997969
  • Synonyms:OG-L002;[1,1'-Biphenyl]-3-ol, 4'-[(1R,2S)-2-aminocyclopropyl]-4'-((1R,2S)-2-Aminocyclopropyl)biphenyl-3-o;OG-L002 [1,1'-Biphenyl]-3-ol, 4'-[(1R,2S)-2-aminocyclopropyl]-;OG-L002 4'-((1S,2R)-2-aminocyclopropyl)-[1,1'-biphenyl]-3-ol 3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol;4'-((1R,2S)-2-Aminocyclopropyl)biphenyl-3-ol;4'-((1R,2S)-2-Aminocyclopropyl)-[1,1'-biphenyl]-3-ol;OGL002;OG L002;OGL-002;CS-830
24 prices
Selected condition:
Brand
  • aablocks
  • AK Scientific
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Tocris
  • Usbiological
Package
  • 25
  • 5
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 100mg
  • 1g
  • Manufactureraablocks
  • Product numberAA009IDC
  • Product descriptionOg-l002 ≥98%
  • Packaging5mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA009IDC
  • Product descriptionOg-l002 ≥98%
  • Packaging10mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA009IDC
  • Product descriptionOg-l002 ≥98%
  • Packaging25mg
  • Price$619
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2610AH
  • Product descriptionOG-L002
  • Packaging2mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2610AH
  • Product descriptionOG-L002
  • Packaging25mg
  • Price$442
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1580
  • Product descriptionOG-L002
  • Packaging10mM(in 1mL DMSO)
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1580
  • Product descriptionOG-L002
  • Packaging5mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1580
  • Product descriptionOG-L002
  • Packaging25mg
  • Price$399
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154743
  • Product descriptionOG-L002 >99%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154743
  • Product descriptionOG-L002 >99%
  • Packaging250mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154743
  • Product descriptionOG-L002 >99%
  • Packaging1g
  • Price$2839
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17471
  • Product descriptionOG-L002 ≥98%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17471
  • Product descriptionOG-L002 ≥98%
  • Packaging5mg
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17471
  • Product descriptionOG-L002 ≥98%
  • Packaging10mg
  • Price$274
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17471
  • Product descriptionOG-L002 ≥98%
  • Packaging25mg
  • Price$553
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0015247
  • Product descriptionOG-L002 99.71%
  • Packaging5mg
  • Price$125
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009IDC Og-l002 ≥98% 5mg $208 2021-12-16 Buy
aablocks AA009IDC Og-l002 ≥98% 10mg $330 2021-12-16 Buy
aablocks AA009IDC Og-l002 ≥98% 25mg $619 2021-12-16 Buy
AK Scientific 2610AH OG-L002 2mg $119 2021-12-16 Buy
AK Scientific 2610AH OG-L002 25mg $442 2021-12-16 Buy
ApexBio Technology B1580 OG-L002 10mM(in 1mL DMSO) $100 2021-12-16 Buy
ApexBio Technology B1580 OG-L002 5mg $103 2021-12-16 Buy
ApexBio Technology B1580 OG-L002 25mg $399 2021-12-16 Buy
Biorbyt Ltd orb154743 OG-L002 >99% 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb154743 OG-L002 >99% 250mg $1504.5 2021-12-16 Buy
Biorbyt Ltd orb154743 OG-L002 >99% 1g $2839 2021-12-16 Buy
Cayman Chemical 17471 OG-L002 ≥98% 1mg $36 2024-03-01 Buy
Cayman Chemical 17471 OG-L002 ≥98% 5mg $155 2024-03-01 Buy
Cayman Chemical 17471 OG-L002 ≥98% 10mg $274 2024-03-01 Buy
Cayman Chemical 17471 OG-L002 ≥98% 25mg $553 2024-03-01 Buy
ChemScene CS-0015247 OG-L002 99.71% 5mg $125 2021-12-16 Buy

Properties

Boiling point :416.7±45.0 °C(Predicted)
Density :1.193±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥22.5 mg/mL in DMSO; ≥6.82 mg/mL in EtOH
form :solid
pka :9.78±0.10(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lysine-specific demethylase 1 (LSD1) is a protein lysine demethylase that specifically demethylates histone H3 lysine 4 (H3K4) and H3K9, resulting in transcriptional repression. Host LSD1 is also recruited by certain viruses to limit H3K9 methylation, which can repress viral genes necessary for infection. OG-L002 is a potent inhibitor of LSD1 (IC50 = 0.02 μM) that less effectively inhibits the monoamine oxidases A (MAO-A) and MAO-B (IC50s = 1.38 and 0.72 μM). It blocks the expression of immediate early (IE) genes of herpes simplex virus (HSV) in HeLa cells but not that of cellular control genes. OG-L002 also reduces the expression of human cytomegalovirus IE genes and adenovirus E1A gene in mammalian cells. It is effective in vivo, repressing HSV primary infection in mice and blocking HSV reactivation from latency in a mouse ganglion explant model.

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