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ChemicalBook >> CAS DataBase List >> OLTIPRAZ

OLTIPRAZ

OLTIPRAZ price.
  • $9 - $3998
  • Product name: OLTIPRAZ
  • CAS: 64224-21-1
  • MF: C8H6N2S3
  • MW: 226.34
  • EINECS:264-736-6
  • MDL Number:MFCD00868499
  • Synonyms:NSC 347901;3H-1,2-Dithiole-3-thione,4-methyl-5-(2-pyrazinyl)-;OLTIPRAZ;4-methyl-5-pyrazinyl-3h-1,2-dithiole-3-thione ;4-methyl-5-pyrazinyl-3h-2-dithiole-3-thione ;5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione ;4-Methyl-5-(2-pyrazinyl)-3H-1,2-dithiole-3-thione;4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione
Price37 Properties Safety Information Description
37 prices
Selected condition：
Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Chemtos
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1G
  • 5g
  • ManufacturerAHH
  • Product numberMT-57499
  • Product descriptionOltipraz 98%
  • Packaging5g
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4440AJ
  • Product descriptionOltipraz
  • Packaging10mg
  • Price$107
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH35120
  • Product description4-Methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione
  • Packaging100mg
  • Price$149.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH35120
  • Product description4-Methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione
  • Packaging500mg
  • Price$456.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003679
  • Product descriptionOLTIPRAZ 95.00%
  • Packaging100MG
  • Price$267.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003679
  • Product descriptionOLTIPRAZ 95.00%
  • Packaging500MG
  • Price$734.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003679
  • Product descriptionOLTIPRAZ 95.00%
  • Packaging1G
  • Price$904.71
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003679
  • Product descriptionOLTIPRAZ 95.00%
  • Packaging5G
  • Price$1941.37
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS462274
  • Product description4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98%
  • Packaging10mg
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS462274
  • Product description4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98%
  • Packaging50mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS462274
  • Product description4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98%
  • Packaging100mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS462274
  • Product description4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98%
  • Packaging250mg
  • Price$47
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS462274
  • Product description4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98%
  • Packaging1g
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546125
  • Product descriptionOltipraz >98%
  • Packaging50mg
  • Price$134.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546125
  • Product descriptionOltipraz >98%
  • Packaging250mg
  • Price$316.2
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15118
  • Product descriptionOltipraz ≥98%
  • Packaging100mg
  • Price$97
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-57499 Oltipraz 98% 5g $680 2021-12-16 Buy
AK Scientific 4440AJ Oltipraz 10mg $107 2021-12-16 Buy
Alfa Aesar H35120 4-Methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione 100mg $149.65 2024-03-01 Buy
Alfa Aesar H35120 4-Methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione 500mg $456.65 2024-03-01 Buy
American Custom Chemicals Corporation API0003679 OLTIPRAZ 95.00% 100MG $267.75 2021-12-16 Buy
American Custom Chemicals Corporation API0003679 OLTIPRAZ 95.00% 500MG $734.8 2021-12-16 Buy
American Custom Chemicals Corporation API0003679 OLTIPRAZ 95.00% 1G $904.71 2021-12-16 Buy
American Custom Chemicals Corporation API0003679 OLTIPRAZ 95.00% 5G $1941.37 2021-12-16 Buy
Arctom AS462274 4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98% 10mg $9 2021-12-16 Buy
Arctom AS462274 4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98% 50mg $15 2021-12-16 Buy
Arctom AS462274 4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98% 100mg $25 2021-12-16 Buy
Arctom AS462274 4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98% 250mg $47 2021-12-16 Buy
Arctom AS462274 4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione ≥98% 1g $123 2021-12-16 Buy
Biorbyt Ltd orb546125 Oltipraz >98% 50mg $134.3 2021-12-16 Buy
Biorbyt Ltd orb546125 Oltipraz >98% 250mg $316.2 2021-12-16 Buy
Cayman Chemical 15118 Oltipraz ≥98% 100mg $97 2024-03-01 Buy
Next Last

Properties

Melting point :165-166
Boiling point :408.1±55.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
RTECS :JP1293000
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :0.18±0.10(Predicted)
form :Solid
color :red
Sensitive :Light Sensitive
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey :CKNAQFVBEHDJQV-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Oltipraz, originally identified as an antischistosomiasis agent, is a potent anticarcinogen in a variety of animal models of cancer at concentrations of ~200 mg/kg. It is an effective inducer of phase I and II detoxifying enzymes, including glutathione S-tranferases, UDP-glucuronosyltransferases, NAD(P)H:quinone oxidoreductase, microsomal epoxide hydrolase, and aflatoxin aldehyde reductase. Induction of these metabolic enzymes by oltipraz has been linked to the transcription factor nuclear factor E2-related factor 2 and its activation of the antioxidant response element. In mice, oltipraz at 150 mg/kg can also induce expression of CYP2B, a gene regulated by the constitutive androstane receptor, a transcription factor important in the detoxification of endobiotic and xenobiotic substances.

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