Olaparib
|
- $28 - $2147.1
- Product name: Olaparib
- CAS: 763113-22-0
- MF: C24H23FN4O3
- MW: 434.46
- EINECS:642-941-5
- MDL Number:MFCD13185161
- Synonyms:1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]piperazin;Olaparid AZD2281;4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]Methyl]-1(2H)-phthalazinone;KU 59436;AZD2281(olaparib)/AZD-2281;AZD2281(olaparib);4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one;Olaparib-D8
63 prices
Selected condition：
Brand
- AccelPharmtech
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1unit
- 5mg
- 10MG
- 20mg
- 25mg
- 50MG
- 2x25mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1G
- 2g
- 5G
- 10G
- 25G
- 10mM(in 1mL DMSO)
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging1G
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging5G
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging10G
- Price$1050
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging25G
- Price$1910
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-3043-M100
- Product descriptionOlaparib ≥95%
- Packaging100mg
- Price$594
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ93043
- Product descriptionOlaparib
- Packaging250mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ93043
- Product descriptionOlaparib
- Packaging1g
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberB673
- Product descriptionOlaparib
- Packaging1g
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024518
- Product descriptionOLAPARIB 95.00%
- Packaging10MG
- Price$154.35
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024518
- Product descriptionOLAPARIB 95.00%
- Packaging50MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging100mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging500mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60045
- Product descriptionOlaparib(AZD2281) ≥98%
- Packaging20mg
- Price$148
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AccelPharmtech | CF1283 | Olaparib 99% | 1G | $130 | 2021-12-16 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99% | 5G | $230 | 2021-12-16 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99% | 10G | $1050 | 2021-12-16 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99% | 25G | $1910 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-3043-M100 | Olaparib ≥95% | 100mg | $594 | 2021-12-16 | Buy |
| AK Scientific | J93043 | Olaparib | 250mg | $49 | 2021-12-16 | Buy |
| AK Scientific | J93043 | Olaparib | 1g | $110 | 2021-12-16 | Buy |
| AK Scientific | B673 | Olaparib | 1g | $300 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024518 | OLAPARIB 95.00% | 10MG | $154.35 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024518 | OLAPARIB 95.00% | 50MG | $721.88 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 10mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 100mg | $160 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 500mg | $480 | 2021-12-16 | Buy |
| Arctom | CFN60045 | Olaparib(AZD2281) ≥98% | 20mg | $148 | 2021-12-16 | Buy |
Properties
Density :1.43
storage temp. :-20°C
solubility :Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)
pka :12.07±0.40(Predicted)
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :FDLYAMZZIXQODN-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C=CC=C2)C(CC2=CC=C(F)C(C(N3CCN(C(C4CC4)=O)CC3)=O)=C2)=NN1
CAS DataBase Reference :763113-22-0
storage temp. :-20°C
solubility :Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)
pka :12.07±0.40(Predicted)
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :FDLYAMZZIXQODN-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C=CC=C2)C(CC2=CC=C(F)C(C(N3CCN(C(C4CC4)=O)CC3)=O)=C2)=NN1
CAS DataBase Reference :763113-22-0
Safety Information
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| Signal word: | Danger | ||||||||||||||||||
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Description
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 μM). It can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and increase cancer cell death.More related product prices
2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4- carboxamide BMN 673 871700-17-3 PF-01367338 Bortezomib 1021298-67-8 59878-57-8 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid Nintedanib Ethanesulfonate Salt PLERIXAFOR Afatinib (BIBW 2992) Crizotinib 4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one 3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid 918504-65-1Related product price
- 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-
carboxamide
$28-4644 - BMN 673
$28-2839 - 871700-17-3
$28-4391.1
Suppliers and manufacturers
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.
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Hefei TianRui Pharmaceutical Chemical Co., Ltd.
SHANDONG BOYUAN PHARMACEUTICAL CO., LTD.
Beijing Hope Pharmaceutical Co., Ltd.
