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ChemicalBook >> CAS DataBase List >> Omarigliptin (MK-3102)

Omarigliptin (MK-3102)

Omarigliptin (MK-3102) price.
  • $55 - $5576
  • Product name: Omarigliptin (MK-3102)
  • CAS: 1226781-44-7
  • MF: C17H20F2N4O3S
  • MW: 398.43
  • EINECS:682-558-0
  • MDL Number:MFCD22573261
  • Synonyms:(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(Methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-aMine;MK-3012;(2S,3R,5S)-2-(2,5-Difluorophenyl)-5-[2-(Methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-aMine (MK-3102 enantioMer);(2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine;OMarigliptin (MK-3102);2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine MK3102;MK-3102 - M10588;MK-3102, >=98%
32 prices
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Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 1000mg
  • ManufacturerAK Scientific
  • Product number9051AF
  • Product descriptionOmarigliptin
  • Packaging2mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115550
  • Product descriptionOmarigliptin 98+%
  • Packaging2mg
  • Price$83
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115550
  • Product descriptionOmarigliptin 98+%
  • Packaging5mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115550
  • Product descriptionOmarigliptin 98+%
  • Packaging10mg
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115550
  • Product descriptionOmarigliptin 98+%
  • Packaging50mg
  • Price$328
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115550
  • Product descriptionOmarigliptin 98+%
  • Packaging1g
  • Price$5576
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5868
  • Product descriptionMK3102
  • Packaging50mg
  • Price$640
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS437410
  • Product descriptionOmarigliptin ≥98%
  • Packaging5mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181402
  • Product descriptionMK-3102 (Omarigliptin ) >98%
  • Packaging100mg
  • Price$569.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181402
  • Product descriptionMK-3102 (Omarigliptin ) >98%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181402
  • Product descriptionMK-3102 (Omarigliptin ) >98%
  • Packaging1000mg
  • Price$1431.4
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21454
  • Product descriptionMK-3102 ≥98%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21454
  • Product descriptionMK-3102 ≥98%
  • Packaging5mg
  • Price$220
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21454
  • Product descriptionMK-3102 ≥98%
  • Packaging10mg
  • Price$395
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21454
  • Product descriptionMK-3102 ≥98%
  • Packaging25mg
  • Price$885
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3948
  • Product descriptionOmarigliptin
  • Packaging2mg
  • Price$55
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9051AF Omarigliptin 2mg $158 2021-12-16 Buy
Ambeed A115550 Omarigliptin 98+% 2mg $83 2021-12-16 Buy
Ambeed A115550 Omarigliptin 98+% 5mg $149 2021-12-16 Buy
Ambeed A115550 Omarigliptin 98+% 10mg $194 2021-12-16 Buy
Ambeed A115550 Omarigliptin 98+% 50mg $328 2021-12-16 Buy
Ambeed A115550 Omarigliptin 98+% 1g $5576 2021-12-16 Buy
ApexBio Technology B5868 MK3102 50mg $640 2021-12-16 Buy
Arctom AS437410 Omarigliptin ≥98% 5mg $148 2021-12-16 Buy
Biorbyt Ltd orb181402 MK-3102 (Omarigliptin ) >98% 100mg $569.5 2021-12-16 Buy
Biorbyt Ltd orb181402 MK-3102 (Omarigliptin ) >98% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb181402 MK-3102 (Omarigliptin ) >98% 1000mg $1431.4 2021-12-16 Buy
Cayman Chemical 21454 MK-3102 ≥98% 1mg $57 2024-03-01 Buy
Cayman Chemical 21454 MK-3102 ≥98% 5mg $220 2024-03-01 Buy
Cayman Chemical 21454 MK-3102 ≥98% 10mg $395 2024-03-01 Buy
Cayman Chemical 21454 MK-3102 ≥98% 25mg $885 2024-03-01 Buy
ChemScene CS-3948 Omarigliptin 2mg $55 2021-12-16 Buy

Properties

Boiling point :529.4±60.0 °C(Predicted)
Density :1.61±0.1 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :insoluble in EtOH; insoluble in H2O; ≥17.15 mg/mL in DMSO
form :solid
pka :9.11±0.60(Predicted)
InChI :InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17-/m1/s1
InChIKey :MKMPWKUAHLTIBJ-ISTRZQFTSA-N
SMILES :[C@H]1(C2=CC(F)=CC=C2F)OC[C@H](N2CC3=CN(S(C)(=O)=O)N=C3C2)C[C@@H]1N
CAS DataBase Reference :1226781-44-7

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Merck earned its first global approval for omarigliptin in Japan in 2015, and phase III development is ongoing in other countries around the globe for this interesting small molecule DPP-4 inhibitor. Interestingly, while most DPP-4 inhibitors used to treat type 2 DM require daily administration, omarigliptin is a weekly treatment. The process-scale synthesis of omarigliptin has been nicely described in an October 2015 paper from the Merck process group.