Pramlintide acetate
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- $100 - $3978
- Product name: Pramlintide acetate
- CAS: 196078-30-5
- MF: C173H273N51O56S2
- MW: 4027.46
- EINECS:251-228-4
- MDL Number:MFCD08460172
- Synonyms:AMYLIN (HUMAN), 25-L-PROLINE-28-L-PROLINE-29-L-PROLINE-, ACETATE (SALT), HYDRATE;pramlintide acetate;pramlintide acetate hydrate;25-L-Proline-28-L-proline-29-L-proline-aMylin (huMan) Acetate Hydrate;AC-137 Acetate Hydrate, SyMlin Acetate Hydrate;Tripo-aMylin Acetate Hydrate;Pramlintide Acetate, Amylin Rat;Pramlintide?Acetate impurity
15 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- DC Chemicals
- TRC
Package
- 1MG
- 2.5mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product numberI376
- Product descriptionPramlintideacetate
- Packaging25mg
- Price$1309
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008261
- Product descriptionPRAMLINTIDE ACETATE HYDRATE 95.00%
- Packaging1MG
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008261
- Product descriptionPRAMLINTIDE ACETATE HYDRATE 95.00%
- Packaging5MG
- Price$3978
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP40890
- Product descriptionPramlintide acetate
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP40890
- Product descriptionPramlintide acetate
- Packaging10mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP40890
- Product descriptionPramlintide acetate
- Packaging25mg
- Price$375
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP40890
- Product descriptionPramlintide acetate
- Packaging50mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP40890
- Product descriptionPramlintide acetate
- Packaging100mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number24093
- Product descriptionPramlintide (acetate hydrate) ≥95%
- Packaging5mg
- Price$242
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24093
- Product descriptionPramlintide (acetate hydrate) ≥95%
- Packaging10mg
- Price$459
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24093
- Product descriptionPramlintide (acetate hydrate) ≥95%
- Packaging25mg
- Price$1087
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24093
- Product descriptionPramlintide (acetate hydrate) ≥95%
- Packaging50mg
- Price$1930
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC11279
- Product descriptionPramlintideAcetate >97%
- Packaging1g
- Price$3100
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP700800
- Product descriptionPramlintideAcetateHydrate
- Packaging2.5mg
- Price$215
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP700800
- Product descriptionPramlintideAcetateHydrate
- Packaging25mg
- Price$1695
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | I376 | Pramlintideacetate | 25mg | $1309 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008261 | PRAMLINTIDE ACETATE HYDRATE 95.00% | 1MG | $1000 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008261 | PRAMLINTIDE ACETATE HYDRATE 95.00% | 5MG | $3978 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP40890 | Pramlintide acetate | 5mg | $100 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP40890 | Pramlintide acetate | 10mg | $170 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP40890 | Pramlintide acetate | 25mg | $375 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP40890 | Pramlintide acetate | 50mg | $550 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP40890 | Pramlintide acetate | 100mg | $850 | 2021-12-16 | Buy |
Cayman Chemical | 24093 | Pramlintide (acetate hydrate) ≥95% | 5mg | $242 | 2024-03-01 | Buy |
Cayman Chemical | 24093 | Pramlintide (acetate hydrate) ≥95% | 10mg | $459 | 2024-03-01 | Buy |
Cayman Chemical | 24093 | Pramlintide (acetate hydrate) ≥95% | 25mg | $1087 | 2024-03-01 | Buy |
Cayman Chemical | 24093 | Pramlintide (acetate hydrate) ≥95% | 50mg | $1930 | 2024-03-01 | Buy |
DC Chemicals | DC11279 | PramlintideAcetate >97% | 1g | $3100 | 2021-12-16 | Buy |
TRC | P700800 | PramlintideAcetateHydrate | 2.5mg | $215 | 2021-12-16 | Buy |
TRC | P700800 | PramlintideAcetateHydrate | 25mg | $1695 | 2021-12-16 | Buy |
Properties
Melting point :>175°C (dec.)
storage temp. :Refrigerator
solubility :Acetic Acid (Slightly), DMSO (Slightly)
form :Solid
color :White to Off-White
CAS DataBase Reference :196078-30-5(CAS DataBase Reference)
storage temp. :Refrigerator
solubility :Acetic Acid (Slightly), DMSO (Slightly)
form :Solid
color :White to Off-White
CAS DataBase Reference :196078-30-5(CAS DataBase Reference)
Safety Information
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Description
Pramlintide acetate is an injectable human amylin analog that has been launched for the treatment of both type 1 and type 2 diabetes, in conjunction with insulin. While it is also a 37-amino acid peptide, it differs from its parent predecessor by the substitution of Ala-25, Ser-28, and Ser-29 with prolines. Not only do these modifications improve the solubility of the peptide, they also eliminate the aggregation observed with amylin, resulting in a stable synthetic analog with retention of biological activity that is suitable for pharmaceutical use. As an indication of potency, Pramlintide acetate inhibits the binding of radioiodinated rat amylin to rat nucleus accumbens membranes with a Ki value of 23 pM. Its mechanism of action mimics amylin; as a neurohormone that is cosecreted with insulin from the pancreatic β cells in response to meals, it is involved in glucose homeostasis. Both peptides lower postprandial glucose levels by inhibiting glucagon and by restraining the vagus-mediated rate of gastric emptying, thereby, slowing intestinal carbohydrate absorption. Furthermore, amylin, orPramlintide acetate, has the added benefit of inducing postprandial satiety resulting in weight loss in the patients with type 2 diabetes. Since Pramlintide acetate slows gastric emptying, it is contraindicated in patients with gastroparesis and in patients taking drugs that alter gastrointestinal motility (anticholinergic agents, such as, atropine) or slow down the intestinal absorption of nutrients (such as α-glucosidase inhibitors). Pramlintide acetate is also contraindicated in patients with hypoglycemic tendencies; due to co-administration with insulin, severe insulin-induced hypoglycemia is a risk. The most commonly reported adverse events include nausea, vomiting, anorexia, headache, abdominal pain, fatigue, dizziness, coughing, and pharyngitis.Related product price
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Suppliers and manufacturers
Alpha Biopharmaceuticals Co., Ltd
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