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ChemicalBook >> CAS DataBase List >> (S)-(+)-Ketoprofen

(S)-(+)-Ketoprofen

(S)-(+)-Ketoprofen price.
  • $5 - $860
  • Product name: (S)-(+)-Ketoprofen
  • CAS: 22161-81-5
  • MF: C16H14O3
  • MW: 254.28
  • EINECS:606-944-5
  • MDL Number:MFCD00673316
  • Synonyms:(+)-hydratropicaci ;(S)-(+)-KETOPROFEN;(S)-(+)-3-BENZOYL-ALPHA-METHYLBENZENE-ACETIC ACID;[S]-2-[3-BENZOYLPHENYL]PROPIONIC ACID;3-(1-Hydrocarboxyethyl)benzophenone;Dexktoprofen;(S)-(+)-3-Benzoyl-α-methylbenzeneacetic acid, (S)-2-(3-Benzoylphenyl)propionic acid;(S)-2-(3-Benzoylphenyl)propanoic acid
26 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 5MG
  • 25mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • 25g
  • ManufacturerAK Scientific
  • Product numberJ92686
  • Product description(S)-(+)-Ketoprofen
  • Packaging5g
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305587
  • Product description(S)-Ketoprofen 98%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305587
  • Product description(S)-Ketoprofen 98%
  • Packaging100mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305587
  • Product description(S)-Ketoprofen 98%
  • Packaging250mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305587
  • Product description(S)-Ketoprofen 98%
  • Packaging1g
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305587
  • Product description(S)-Ketoprofen 98%
  • Packaging5g
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305587
  • Product description(S)-Ketoprofen 98%
  • Packaging25g
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000681
  • Product descriptionDEXKETOPROFEN 95.00%
  • Packaging100MG
  • Price$445
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0027406
  • Product description(S)-KETOPROFEN 95.00%
  • Packaging5MG
  • Price$454.95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000681
  • Product descriptionDEXKETOPROFEN 95.00%
  • Packaging1G
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3334
  • Product description(S)-Ketoprofen
  • Packaging10mM(in 1mL DMSO)
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3334
  • Product description(S)-Ketoprofen
  • Packaging500mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3334
  • Product description(S)-Ketoprofen
  • Packaging1g
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3334
  • Product description(S)-Ketoprofen
  • Packaging5g
  • Price$271
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBK166230
  • Product description(S)-(+)-Ketoprofen
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16407
  • Product description(S)-Ketoprofen ≥98%
  • Packaging100mg
  • Price$32
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J92686 (S)-(+)-Ketoprofen 5g $49 2021-12-16 Buy
Ambeed A305587 (S)-Ketoprofen 98% 25mg $5 2021-12-16 Buy
Ambeed A305587 (S)-Ketoprofen 98% 100mg $8 2021-12-16 Buy
Ambeed A305587 (S)-Ketoprofen 98% 250mg $12 2021-12-16 Buy
Ambeed A305587 (S)-Ketoprofen 98% 1g $28 2021-12-16 Buy
Ambeed A305587 (S)-Ketoprofen 98% 5g $79 2021-12-16 Buy
Ambeed A305587 (S)-Ketoprofen 98% 25g $275 2021-12-16 Buy
American Custom Chemicals Corporation INB0000681 DEXKETOPROFEN 95.00% 100MG $445 2021-12-16 Buy
American Custom Chemicals Corporation API0027406 (S)-KETOPROFEN 95.00% 5MG $454.95 2021-12-16 Buy
American Custom Chemicals Corporation INB0000681 DEXKETOPROFEN 95.00% 1G $470 2021-12-16 Buy
ApexBio Technology C3334 (S)-Ketoprofen 10mM(in 1mL DMSO) $42 2021-12-16 Buy
ApexBio Technology C3334 (S)-Ketoprofen 500mg $54 2021-12-16 Buy
ApexBio Technology C3334 (S)-Ketoprofen 1g $81 2021-12-16 Buy
ApexBio Technology C3334 (S)-Ketoprofen 5g $271 2021-12-16 Buy
Biosynth Carbosynth BK166230 (S)-(+)-Ketoprofen 100mg $50 2021-12-16 Buy
Cayman Chemical 16407 (S)-Ketoprofen ≥98% 100mg $32 2024-03-01 Buy

Properties

Melting point :75-78 °C(lit.)
Boiling point :431.3±28.0 °C(Predicted)
Density :1.198±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :insoluble in H2O; ≥10.6 mg/mL in DMSO; ≥20.55 mg/mL in EtOH
form :White solid.
pka :4.23±0.10(Predicted)
color :White to off-white
optical activity :[α]22/D +49°, c = 1 in methanol
CAS DataBase Reference :22161-81-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ketoprofen is a non-selective, non-steroidal, anti-inflammatory drug exhibiting IC50 values of 0.5 and 2.33 μM for human recombinant COX-1 and COX-2 , respectively. Ketoprofen is commonly used in vivo as a racemic mixture of (R)- and (S)-enantiomers. (S)-Ketoprofen is a potent inhibitor of COX-1 and COX-2 (IC50s = 1.9 and 27 nM, respectively), whereas the (R)-enantiomer is 100 to 1,000 times less potent. Notably, (S)-ketoprofen is known to be formed from the (R)-enantiomer in several animal species, except in humans and guinea pigs. Also, the pharmacokinetics of ketoprofen enantiomers and their glucuronide metabolites are altered in humans with rheumatoid arthritis or renal disease.

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