SIRTINOL
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- $18 - $1380
- Product name: SIRTINOL
- CAS: 410536-97-9
- MF: C26H22N2O2
- MW: 394.47
- EINECS:
- MDL Number:MFCD00810186
- Synonyms:2-[(2-HYDROXYNAPHTHALEN-1-YLMETHYLENE)AMINO]-N-(1-PHENETHYL)BENZAMIDE;SIRTINOL;SIR TWO INHIBITOR NAPHTHOL;(E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide;2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)benzamide;2-{[(2-hydroxynaphthalen-1-yl)Methylidene]aMino}-N-(2-phenylethyl)benzaMide;{2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]}-N-(1-phenethyl)benzamide (Sirtinol);Sirtinol - CAS 410536-97-9 - Calbiochem
54 prices
Selected condition：
Brand
- Abosyn
- Adipogen Life Sciences
- AHH
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Aronis compounds
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynChem
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 10
- 50
- 25mg
- 0.025g
- 50mg
- 100mg
- 10mM(in 1mL DMSO)
- 250MG
- 0.25g
- 1G
- 5G
- 10g
- ManufacturerAbosyn
- Product number61-0141
- Product description(E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide 95-98%
- Packaging0.25g
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0055-M001
- Product descriptionSirtinol ≥98%(NMR)
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0055-M025
- Product descriptionSirtinol ≥98%(NMR)
- Packaging25mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-15353
- Product description2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide 95%
- Packaging0.025g
- Price$418
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberW6155
- Product descriptionSirtinol
- Packaging10mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64486
- Product descriptionSirtinol
- Packaging10mg
- Price$202
- Updated2023-06-20
- Buy
- ManufacturerAmbeed
- Product numberA204147
- Product descriptionSirtinol 98+%
- Packaging1mg
- Price$18
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA204147
- Product descriptionSirtinol 98+%
- Packaging5mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA204147
- Product descriptionSirtinol 98+%
- Packaging10mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA204147
- Product descriptionSirtinol 98+%
- Packaging50mg
- Price$258
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0003801
- Product descriptionSirtinol 95.00%
- Packaging1MG
- Price$400.63
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0003801
- Product descriptionSirtinol 95.00%
- Packaging250MG
- Price$559
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0003801
- Product descriptionSirtinol 95.00%
- Packaging1G
- Price$798
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4183
- Product descriptionSirtinol
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4183
- Product descriptionSirtinol
- Packaging10mM(in 1mL DMSO)
- Price$61
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4183
- Product descriptionSirtinol
- Packaging25mg
- Price$190
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Abosyn | 61-0141 | (E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide 95-98% | 0.25g | $225 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-0055-M001 | Sirtinol ≥98%(NMR) | 1mg | $30 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-0055-M025 | Sirtinol ≥98%(NMR) | 25mg | $165 | 2021-12-16 | Buy |
| AHH | MT-15353 | 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide 95% | 0.025g | $418 | 2021-12-16 | Buy |
| AK Scientific | W6155 | Sirtinol | 10mg | $104 | 2021-12-16 | Buy |
| Alfa Aesar | J64486 | Sirtinol | 10mg | $202 | 2023-06-20 | Buy |
| Ambeed | A204147 | Sirtinol 98+% | 1mg | $18 | 2021-12-16 | Buy |
| Ambeed | A204147 | Sirtinol 98+% | 5mg | $56 | 2021-12-16 | Buy |
| Ambeed | A204147 | Sirtinol 98+% | 10mg | $84 | 2021-12-16 | Buy |
| Ambeed | A204147 | Sirtinol 98+% | 50mg | $258 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0003801 | Sirtinol 95.00% | 1MG | $400.63 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0003801 | Sirtinol 95.00% | 250MG | $559 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0003801 | Sirtinol 95.00% | 1G | $798 | 2021-12-16 | Buy |
| ApexBio Technology | A4183 | Sirtinol | 5mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4183 | Sirtinol | 10mM(in 1mL DMSO) | $61 | 2021-12-16 | Buy |
| ApexBio Technology | A4183 | Sirtinol | 25mg | $190 | 2021-12-16 | Buy |
Properties
Melting point :119-120℃
Boiling point :659.2±50.0 °C(Predicted)
Density :1.16
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml).
form :Yellow solid
pka :7.85±0.50(Predicted)
color :Pale yellow
Water Solubility :Soluble in water, DMSO and methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Boiling point :659.2±50.0 °C(Predicted)
Density :1.16
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml).
form :Yellow solid
pka :7.85±0.50(Predicted)
color :Pale yellow
Water Solubility :Soluble in water, DMSO and methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Sirtinol is a cell-permeable inhibitor of sirtuin NAD+-dependent deacetylases, inhibiting the yeast sirtuin Sir2p with an IC50 value of 68 μM and the human sirtuins SIRT1 and SIRT2 with IC50 values of 131 and 38 μM, respectively. It does not alter HDAC1 activity. Sirtinol inhibits the growth of cancer cells and suppresses inflammatory signaling in human dermal microvascular endothelial cells. In plants, sirtinol can be metabolized to 2-hydroxy-1-naphthoic acid, which activates auxin signaling and alters plant growth and development.Related product price
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