TG003
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- $23 - $2498
- Product name: TG003
- CAS: 300801-52-9
- MF: C13H15NO2S
- MW: 249.33
- EINECS:
- MDL Number:MFCD00624584
- Synonyms:Cdc2-Like Kinase Inhibitor, TG003;TG003/TG-003;2-Propanone,1-(3-ethyl-5-Methoxy-2(3H)-benzothiazolylidene)-;(1Z)-1-(3-Ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one;1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone;(Z)-1-(3-ethyl-5-methoxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one;CS-955;CS-1704
20 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- BroadPharm
- Cayman Chemical
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3656-M005
- Product descriptionTG003 ≥98%
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3656-M025
- Product descriptionTG003 ≥98%
- Packaging25mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2753AH
- Product description(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one
- Packaging1mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2753AH
- Product description(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one
- Packaging50mg
- Price$664
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64690
- Product descriptionCdc2-Like Kinase Inhibitor, TG003
- Packaging5mg
- Price$85.1
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64690
- Product descriptionCdc2-Like Kinase Inhibitor, TG003
- Packaging50mg
- Price$551
- Updated2023-06-20
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001257
- Product descriptionTG003 95.00%
- Packaging1MG
- Price$428
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001257
- Product descriptionTG003 95.00%
- Packaging5MG
- Price$716.56
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001257
- Product descriptionTG003 95.00%
- Packaging25MG
- Price$1098.14
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-20670
- Product description1-(3-ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone 98%
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10398
- Product descriptionTG003 ≥95%
- Packaging1mg
- Price$23
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10398
- Product descriptionTG003 ≥95%
- Packaging5mg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10398
- Product descriptionTG003 ≥95%
- Packaging10mg
- Price$177
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10398
- Product descriptionTG003 ≥95%
- Packaging25mg
- Price$384
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC8932
- Product descriptionTG003 >98%
- Packaging1g
- Price$1400
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number144988
- Product description(Z)-1-(3-Ethyl-5-methoxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one 95%
- Packaging50mg
- Price$1573
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3656-M005 | TG003 ≥98% | 5mg | $80 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3656-M025 | TG003 ≥98% | 25mg | $280 | 2021-12-16 | Buy |
| AK Scientific | 2753AH | (Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one | 1mg | $73 | 2021-12-16 | Buy |
| AK Scientific | 2753AH | (Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one | 50mg | $664 | 2021-12-16 | Buy |
| Alfa Aesar | J64690 | Cdc2-Like Kinase Inhibitor, TG003 | 5mg | $85.1 | 2023-06-20 | Buy |
| Alfa Aesar | J64690 | Cdc2-Like Kinase Inhibitor, TG003 | 50mg | $551 | 2023-06-20 | Buy |
| American Custom Chemicals Corporation | KIN0001257 | TG003 95.00% | 1MG | $428 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001257 | TG003 95.00% | 5MG | $716.56 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001257 | TG003 95.00% | 25MG | $1098.14 | 2021-12-16 | Buy |
| BroadPharm | BP-20670 | 1-(3-ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone 98% | 5mg | $80 | 2021-12-16 | Buy |
| Cayman Chemical | 10398 | TG003 ≥95% | 1mg | $23 | 2024-03-01 | Buy |
| Cayman Chemical | 10398 | TG003 ≥95% | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 10398 | TG003 ≥95% | 10mg | $177 | 2024-03-01 | Buy |
| Cayman Chemical | 10398 | TG003 ≥95% | 25mg | $384 | 2024-03-01 | Buy |
| DC Chemicals | DC8932 | TG003 >98% | 1g | $1400 | 2021-12-16 | Buy |
| Matrix Scientific | 144988 | (Z)-1-(3-Ethyl-5-methoxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one 95% | 50mg | $1573 | 2021-12-16 | Buy |
Properties
Melting point :132-132.5 °C
Boiling point :386.0±42.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 33 mg/mL
form :solid
pka :-1.76±0.20(Predicted)
color :pale yellow
Sensitive :Light Sensitive
Boiling point :386.0±42.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 33 mg/mL
form :solid
pka :-1.76±0.20(Predicted)
color :pale yellow
Sensitive :Light Sensitive
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Cdc2-like kinase (Clk), among a number of other kinases, phosphorylates serine/arginine-rich proteins which play a role in alternative splicing of pre-mRNA. The Clk family consists of four members, which include Clk1/Sty and Clk2-4. TG003 is a novel benzothiazole compound that demonstrates potent inhibition of Clk1/Sty and Clk4 with IC50 values of 20 and 15 nM, respectively. TG003 exhibits considerably weaker inhibition of Clk2 and Clk3 (IC50 = 200 nM and >10 μM, respectively). Through suppression of Clk-mediated phosphorylation, TG003 inhibits SF2/ASF-dependent splicing of β-globin pre-mRNA at 1 μM in vitro. At 10 μM, TG003 rescues the embryonic defects induced by excessive Clk activity in Xenopus.More related product prices
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