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ChemicalBook >> TIMTEC-BB SBB005393

TIMTEC-BB SBB005393

TIMTEC-BB SBB005393 price.
  • $40 - $34400
  • Product name: TIMTEC-BB SBB005393
  • CAS: 72214-67-6
  • MF: C8H9Cl3N2S
  • MW: 271.6
  • EINECS:
  • MDL Number:MFCD00035047
  • Synonyms:TIMTEC-BB SBB005393;(2,4-Dichlorophenyl)carbamimidothioic acid methyl ester hydrochloride;2-(2,4-Dichlorobenzyl)-2-thiopseudourea hydrochloride;Rb/Raf-1 disruptor 251 hydrochloride;S-(2,4-Dichlorobenzyl)-isothiouronium hydrochloride;(2,4-dichlorophenyl)methylsulfanylformamidine hydrochloride;(2,4-dichlorophenyl)methylsulfanylmethanimidamide hydrochloride;[(2,4-dichlorobenzyl)thio]formamidine hydrochloride
Price18 Properties Safety Information Description
18 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • ChemScene
  • Matrix Scientific
  • Sigma-Aldrich
  • TRC
Package
  • 5MG
  • 10mg
  • 25MG
  • 250mg
  • 0.500g
  • 500mg
  • 1g
  • 2g
  • 5G
  • ManufacturerAK Scientific
  • Product number5509BB
  • Product description2,4-Dichlorobenzylimidothiocarbamatehydrochloride
  • Packaging500mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001077
  • Product descriptionRRD-251 HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$434
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001077
  • Product descriptionRRD-251 HYDROCHLORIDE 95.00%
  • Packaging25MG
  • Price$536
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001077
  • Product descriptionRRD-251 HYDROCHLORIDE 95.00%
  • Packaging5G
  • Price$34400
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD132494
  • Product description2,4-Dichlorobenzyl imidothiocarbamate hydrochloride
  • Packaging250mg
  • Price$57.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD132494
  • Product description2,4-Dichlorobenzyl imidothiocarbamate hydrochloride
  • Packaging500mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD132494
  • Product description2,4-Dichlorobenzyl imidothiocarbamate hydrochloride
  • Packaging1g
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD132494
  • Product description2,4-Dichlorobenzyl imidothiocarbamate hydrochloride
  • Packaging2g
  • Price$289
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD132494
  • Product description2,4-Dichlorobenzyl imidothiocarbamate hydrochloride
  • Packaging5G
  • Price$578
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0083583
  • Product descriptionRRD-251
  • Packaging5mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number156526
  • Product description2,4-Dichlorobenzyl imidothiocarbamate hydrochloride
  • Packaging0.500g
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number156526
  • Product description2,4-Dichlorobenzyl imidothiocarbamate hydrochloride
  • Packaging1g
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number156526
  • Product description2,4-Dichlorobenzyl imidothiocarbamate hydrochloride
  • Packaging5g
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberR7532
  • Product descriptionRRD-251 hydrochloride ≥98% (HPLC)
  • Packaging5mg
  • Price$54.3
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number559270
  • Product descriptionRRD-251 hydrochloride
  • Packaging25mg
  • Price$143
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberR7532
  • Product descriptionRRD-251 hydrochloride ≥98% (HPLC)
  • Packaging25mg
  • Price$208
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5509BB 2,4-Dichlorobenzylimidothiocarbamatehydrochloride 500mg $266 2021-12-16 Buy
American Custom Chemicals Corporation INB0001077 RRD-251 HYDROCHLORIDE 95.00% 5MG $434 2021-12-16 Buy
American Custom Chemicals Corporation INB0001077 RRD-251 HYDROCHLORIDE 95.00% 25MG $536 2021-12-16 Buy
American Custom Chemicals Corporation INB0001077 RRD-251 HYDROCHLORIDE 95.00% 5G $34400 2021-12-16 Buy
Biosynth Carbosynth FD132494 2,4-Dichlorobenzyl imidothiocarbamate hydrochloride 250mg $57.5 2021-12-16 Buy
Biosynth Carbosynth FD132494 2,4-Dichlorobenzyl imidothiocarbamate hydrochloride 500mg $100 2021-12-16 Buy
Biosynth Carbosynth FD132494 2,4-Dichlorobenzyl imidothiocarbamate hydrochloride 1g $170 2021-12-16 Buy
Biosynth Carbosynth FD132494 2,4-Dichlorobenzyl imidothiocarbamate hydrochloride 2g $289 2021-12-16 Buy
Biosynth Carbosynth FD132494 2,4-Dichlorobenzyl imidothiocarbamate hydrochloride 5G $578 2021-12-16 Buy
ChemScene CS-0083583 RRD-251 5mg $250 2021-12-16 Buy
Matrix Scientific 156526 2,4-Dichlorobenzyl imidothiocarbamate hydrochloride 0.500g $160 2021-12-16 Buy
Matrix Scientific 156526 2,4-Dichlorobenzyl imidothiocarbamate hydrochloride 1g $200 2021-12-16 Buy
Matrix Scientific 156526 2,4-Dichlorobenzyl imidothiocarbamate hydrochloride 5g $700 2021-12-16 Buy
Sigma-Aldrich R7532 RRD-251 hydrochloride ≥98% (HPLC) 5mg $54.3 2024-03-01 Buy
Sigma-Aldrich 559270 RRD-251 hydrochloride 25mg $143 2022-05-15 Buy
Sigma-Aldrich R7532 RRD-251 hydrochloride ≥98% (HPLC) 25mg $208 2024-03-01 Buy
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Properties

Melting point :222-227 °C
storage temp. :room temp
solubility :DMSO: >10mg/mL
form :White solid
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

Description

RRD-251 hydrochloride is a reversible, potent, and selective disruptor of Rb/Raf-1 interaction. The retinoblastoma tumor suppressor protein (Rb) controls the G1-S boundary by repressing the transcriptional activity of the E2F family of transcription factors. Raf-1 kinase binds and phosphorylates Rb early in the G1 phase. RRD-251 significantly inhibits angiogenesis and tumor growth in vivo in an Rb-dependent manner. RRD-251 does not inhibit the binding of B-Raf to Rb and Raf-1 to Mek1/2. Also, RRD-251 does not affect the kinase activities associated with cyclin D, cyclin E, or Raf-1.

Suppliers and manufacturers

Tianjin Kailiqi Biotechnology Co., Ltd. Nanjing Shizhou Biology Technology Co.,Ltd Shanghai Xiushi Biomedical Co., LTD Nanjing Shizhou Biology Technology Co.,Ltd Shanghai Universal Biotech Co.,Ltd TargetMol Chemicals Inc. Suzhou Zhixin Biotechnology Co., Ltd. Nantong QuanYi Biotechnology Co., Ltd RD International Technology Co., Limited Carbosynth