Tivozanib (hydrate)
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- $54 - $1600
- Product name: Tivozanib (hydrate)
- CAS: 682745-40-0
- MF: C22H21ClN4O6
- MW: 472.88
- EINECS:
- MDL Number:
- Synonyms:Tivozanib (hydrate);N-[2-chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)-urea,monohydrate
7 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
Package
- 5mg
- 003
- 1mg
- 10mg
- ManufacturerAK Scientific
- Product number8654DU
- Product descriptionVEGFRTyrosineKinaseInhibitorIV
- Packaging5mg
- Price$221
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8654DU
- Product descriptionVEGFRTyrosineKinaseInhibitorIV
- Packaging10mg
- Price$262
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3415
- Product descriptionTivozanib(hydrate)
- Packaging10mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18493
- Product descriptionTivozanib (hydrate) ≥95%
- Packaging1mg
- Price$54
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18493
- Product descriptionTivozanib (hydrate) ≥95%
- Packaging5mg
- Price$117
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18493
- Product descriptionTivozanib (hydrate) ≥95%
- Packaging10mg
- Price$155
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product number013388
- Product descriptionTivozanib(hydrate)
- Packaging003
- Price$1600
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8654DU | VEGFRTyrosineKinaseInhibitorIV | 5mg | $221 | 2021-12-16 | Buy |
| AK Scientific | 8654DU | VEGFRTyrosineKinaseInhibitorIV | 10mg | $262 | 2021-12-16 | Buy |
| ApexBio Technology | C3415 | Tivozanib(hydrate) | 10mg | $166 | 2021-12-16 | Buy |
| Cayman Chemical | 18493 | Tivozanib (hydrate) ≥95% | 1mg | $54 | 2024-03-01 | Buy |
| Cayman Chemical | 18493 | Tivozanib (hydrate) ≥95% | 5mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 18493 | Tivozanib (hydrate) ≥95% | 10mg | $155 | 2024-03-01 | Buy |
| DC Chemicals | 013388 | Tivozanib(hydrate) | 003 | $1600 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :≤25mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid
solubility :≤25mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid
Safety Information
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Description
Tivozanib is an orally available, selective VEGFR inhibitor with IC50 values of 0.21, 0.16, and 0.24 nM for VEGFR1, VEGFR2, and VEGFR3, respectively. It can also inhibit c-Kit and PDGFRβ with IC50 values of 1.63 and 1.72 nM, respectively. When administered to athymic rats, tivozanib was shown to decrease the microvessel density within tumor xenografts and attenuate VEGFR2 phosphorylation levels in tumor endothelium. It also displays antitumor activity against a wide variety of human tumor xenografts, including lung, breast, colon, ovarian, pancreas, and prostate cancer.More related product prices
905854-02-6 N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)urea