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ChemicalBook >> CAS DataBase List >> Vorapaxar

Vorapaxar

Vorapaxar price.
  • $28 - $2000
  • Product name: Vorapaxar
  • CAS: 618385-01-6
  • MF: C29H33FN2O4
  • MW: 492.58
  • EINECS:
  • MDL Number:MFCD16038876
  • Synonyms:Vorapaxar;Vorapaxar (SCH 530348);Voarapaxar;Ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]vinyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamate;[(1R,3AR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-me;Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester;CS-1663;CS-2015
21 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1unit
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberY1927
  • Product descriptionVorapaxar
  • Packaging1mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ96880
  • Product descriptionVorapaxar
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ96880
  • Product descriptionVorapaxar
  • Packaging25mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007774
  • Product descriptionVORAPAXAR 95.00%
  • Packaging5MG
  • Price$341
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8809
  • Product descriptionVorapaxar
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8809
  • Product descriptionVorapaxar
  • Packaging5mg
  • Price$137
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8809
  • Product descriptionVorapaxar
  • Packaging10mM(in 1mL DMSO)
  • Price$141
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8809
  • Product descriptionVorapaxar
  • Packaging10mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8809
  • Product descriptionVorapaxar
  • Packaging25mg
  • Price$475
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8809
  • Product descriptionVorapaxar
  • Packaging50mg
  • Price$713
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23119
  • Product descriptionVorapaxar ≥98%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23119
  • Product descriptionVorapaxar ≥98%
  • Packaging5mg
  • Price$208
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM141596
  • Product description[(1R,3AR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-carbamicacidethylester 98%
  • Packaging50mg
  • Price$491
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5527
  • Product descriptionVorapaxar 99.85%
  • Packaging5mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5527
  • Product descriptionVorapaxar 99.85%
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5527
  • Product descriptionVorapaxar 99.85%
  • Packaging25mg
  • Price$600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y1927 Vorapaxar 1mg $51 2021-12-16 Buy
AK Scientific J96880 Vorapaxar 10mg $288 2021-12-16 Buy
AK Scientific J96880 Vorapaxar 25mg $600 2021-12-16 Buy
American Custom Chemicals Corporation API0007774 VORAPAXAR 95.00% 5MG $341 2021-12-16 Buy
ApexBio Technology A8809 Vorapaxar 1unit $28 2021-12-16 Buy
ApexBio Technology A8809 Vorapaxar 5mg $137 2021-12-16 Buy
ApexBio Technology A8809 Vorapaxar 10mM(in 1mL DMSO) $141 2021-12-16 Buy
ApexBio Technology A8809 Vorapaxar 10mg $252 2021-12-16 Buy
ApexBio Technology A8809 Vorapaxar 25mg $475 2021-12-16 Buy
ApexBio Technology A8809 Vorapaxar 50mg $713 2021-12-16 Buy
Cayman Chemical 23119 Vorapaxar ≥98% 1mg $57 2024-03-01 Buy
Cayman Chemical 23119 Vorapaxar ≥98% 5mg $208 2024-03-01 Buy
Chemenu CM141596 [(1R,3AR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-carbamicacidethylester 98% 50mg $491 2021-12-16 Buy
ChemScene CS-5527 Vorapaxar 99.85% 5mg $168 2021-12-16 Buy
ChemScene CS-5527 Vorapaxar 99.85% 10mg $288 2021-12-16 Buy
ChemScene CS-5527 Vorapaxar 99.85% 25mg $600 2021-12-16 Buy

Properties

Boiling point :676.0±55.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Store at -20° C
solubility :≥24.65 mg/mL in DMSO; insoluble in H2O; ≥10.64 mg/mL in EtOH with ultrasonic
form :solid
pka :12.49±0.60(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P309+P311 IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P314 Get medical advice/attention if you feel unwell.
P391 Collect spillage. Hazardous to the aquatic environment
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Vorapaxar is an orally bioavailable competitive antagonist of the proteinase-activated receptor (PAR1; Ki = 8.1 nM), also known as the thrombin receptor. It is selective for PAR1 over other PARs, as well as a number of GPCRs, ion channels, and receptors. It inhibits platelet aggregation induced by thrombin and haTRAP (IC50s = 47 and 25 nM, respectively). Vorapaxar (0.1 mg/kg, i.v.) completely inhibits platelet aggregation in cynomolgus monkeys ex vivo. Formulations containing vorapaxar are used in the prevention of thrombotic cardiovascular events.

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