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ChemicalBook >> CAS DataBase List >> ZM 39923 HCl

ZM 39923 HCl

ZM 39923 HCl price.
  • $44 - $1200
  • Product name: ZM 39923 HCl
  • CAS: 1021868-92-7
  • MF: C23H26ClNO
  • MW: 367.91164
  • EINECS:
  • MDL Number:
  • Synonyms:1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-, hydrochloride (1:1);3-[(1-Methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-1-propanone hydrochloride;N-benzyl-N-isopropyl-3-(2-naphthyl)but-3-en-1-amine,hydrochloride;ZM 39923 HCL 50MG;-1-(naphthalen-2-yl);3-(Benzyl(isopropyl);propan-1-one hydrochloride;ZM 39923 HCl, ≥98%
19 prices
Selected condition:
Brand
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAmbeed
  • Product numberA107403
  • Product descriptionZM 39923 hydrochloride 97%
  • Packaging5mg
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107403
  • Product descriptionZM 39923 hydrochloride 97%
  • Packaging10mg
  • Price$196
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107403
  • Product descriptionZM 39923 hydrochloride 97%
  • Packaging50mg
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107403
  • Product descriptionZM 39923 hydrochloride 97%
  • Packaging250mg
  • Price$730
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4151
  • Product descriptionZM39923HCl
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4151
  • Product descriptionZM39923HCl
  • Packaging10mM(in 1mL DMSO)
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4151
  • Product descriptionZM39923HCl
  • Packaging50mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16729
  • Product descriptionZM 39923 (hydrochloride) ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16729
  • Product descriptionZM 39923 (hydrochloride) ≥98%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16729
  • Product descriptionZM 39923 (hydrochloride) ≥98%
  • Packaging10mg
  • Price$172
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM140445
  • Product description3-(benzyl(isopropyl)amino)-1-(naphthalen-2-yl)propan-1-onehydrochloride 97%
  • Packaging50mg
  • Price$204
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4951
  • Product descriptionZM 39923 hydrochloride 99.86%
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4951
  • Product descriptionZM 39923 hydrochloride 99.86%
  • Packaging50mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12186217
  • Product descriptionZM 39923 hydrochloride 97%
  • Packaging50mg
  • Price$389
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7667
  • Product descriptionZM 39923 hydrochloride >98%
  • Packaging100mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7667
  • Product descriptionZM 39923 hydrochloride >98%
  • Packaging250mg
  • Price$600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A107403 ZM 39923 hydrochloride 97% 5mg $131 2021-12-16 Buy
Ambeed A107403 ZM 39923 hydrochloride 97% 10mg $196 2021-12-16 Buy
Ambeed A107403 ZM 39923 hydrochloride 97% 50mg $432 2021-12-16 Buy
Ambeed A107403 ZM 39923 hydrochloride 97% 250mg $730 2021-12-16 Buy
ApexBio Technology A4151 ZM39923HCl 10mg $90 2021-12-16 Buy
ApexBio Technology A4151 ZM39923HCl 10mM(in 1mL DMSO) $99 2021-12-16 Buy
ApexBio Technology A4151 ZM39923HCl 50mg $290 2021-12-16 Buy
Cayman Chemical 16729 ZM 39923 (hydrochloride) ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 16729 ZM 39923 (hydrochloride) ≥98% 5mg $109 2024-03-01 Buy
Cayman Chemical 16729 ZM 39923 (hydrochloride) ≥98% 10mg $172 2024-03-01 Buy
Chemenu CM140445 3-(benzyl(isopropyl)amino)-1-(naphthalen-2-yl)propan-1-onehydrochloride 97% 50mg $204 2021-12-16 Buy
ChemScene CS-4951 ZM 39923 hydrochloride 99.86% 10mg $108 2021-12-16 Buy
ChemScene CS-4951 ZM 39923 hydrochloride 99.86% 50mg $360 2021-12-16 Buy
Crysdot CD12186217 ZM 39923 hydrochloride 97% 50mg $389 2021-12-16 Buy
DC Chemicals DC7667 ZM 39923 hydrochloride >98% 100mg $300 2021-12-16 Buy
DC Chemicals DC7667 ZM 39923 hydrochloride >98% 250mg $600 2021-12-16 Buy

Properties

storage temp. :Inert atmosphere,Room Temperature
solubility :≥7.74 mg/mL in EtOH with gentle warming and ultrasonic; ≥9.2 mg/mL in DMSO
form :solid
color :White to off-white
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Janus kinases (JAKs) are non-receptor kinases that mediate signaling through cytokine receptors, often to members of the signal transducer and activator of transcription (Stat) family. ZM 39923 is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 μM, respectively). In the absence of the reducing agent dithiothreitol, ZM 39923 also inhibits human tissue transglutaminase 2 (TGM2) and the transglutaminase Factor XIIIa (IC50s= 10 and 25 nM, respectively). It breaks down in neutral buffer to form ZM 449829, which is also an inhibitor of JAK3, TGM2, and Factor XIIIa.

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