Zoledronic acid hydrate
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- $6 - $486
- Product name: Zoledronic acid hydrate
- CAS: 165800-06-6
- MF: C5H12N2O8P2
- MW: 290.1
- EINECS:
- MDL Number:MFCD08448695
- Synonyms:[1-HYDROXY-(1H-IMIDAZOL-1-YL)-PHOSPHONOETHYL] PHOSPHONIC ACID MONOHYDRATE;(1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid hydrate;(1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid monohydrate;PHOSPHONIC ACID, [1-HYDROXY-2-(1H-IMIDAZOL-1-YL)ETHYLIDENE]BIS-, MONOHYDRATE;zoledronic acid hydrate;ZoledronicacidforInjection;[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate;P,P′-[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid monohydrate
37 prices
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Brand
- Abosyn
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 10MG
- 25mg
- 50mg
- 100mg
- 0.1g
- 150mg
- 250mg
- 1g
- 5g
- 25g
- ManufacturerAbosyn
- Product number61-10991
- Product description(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 95-98%
- Packaging1g
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerAbosyn
- Product number61-10991
- Product description(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 95-98%
- Packaging5g
- Price$486
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-21417
- Product descriptionPhosphonicacid,[1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-,monohydrate 98%
- Packaging0.1g
- Price$475
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberH683
- Product descriptionZoledronic Acid Monohydrate
- Packaging5g
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA211103
- Product description(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98%
- Packaging50mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA211103
- Product description(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98%
- Packaging100mg
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA211103
- Product description(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98%
- Packaging250mg
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA211103
- Product description(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98%
- Packaging1g
- Price$41
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA211103
- Product description(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98%
- Packaging5g
- Price$109
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015608
- Product descriptionZOLEDRONIC ACID MONOHYDRATE 95.00%
- Packaging10MG
- Price$139.65
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS025691
- Product descriptionZoledronic Acid Monohydrate 98%
- Packaging50mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS025691
- Product descriptionZoledronic Acid Monohydrate 98%
- Packaging100mg
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS025691
- Product descriptionZoledronic Acid Monohydrate 98%
- Packaging250mg
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS025691
- Product descriptionZoledronic Acid Monohydrate 98%
- Packaging1g
- Price$41
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS025691
- Product descriptionZoledronic Acid Monohydrate 98%
- Packaging5g
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1715H
- Product descriptionZoledronic Acid Hydrate
- Packaging100mg
- Price$39
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Abosyn | 61-10991 | (1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 95-98% | 1g | $54 | 2021-12-16 | Buy |
| Abosyn | 61-10991 | (1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 95-98% | 5g | $486 | 2021-12-16 | Buy |
| AHH | MT-21417 | Phosphonicacid,[1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-,monohydrate 98% | 0.1g | $475 | 2021-12-16 | Buy |
| AK Scientific | H683 | Zoledronic Acid Monohydrate | 5g | $300 | 2021-12-16 | Buy |
| Ambeed | A211103 | (1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98% | 50mg | $6 | 2021-12-16 | Buy |
| Ambeed | A211103 | (1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98% | 100mg | $11 | 2021-12-16 | Buy |
| Ambeed | A211103 | (1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98% | 250mg | $16 | 2021-12-16 | Buy |
| Ambeed | A211103 | (1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98% | 1g | $41 | 2021-12-16 | Buy |
| Ambeed | A211103 | (1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonicacidhydrate 98% | 5g | $109 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0015608 | ZOLEDRONIC ACID MONOHYDRATE 95.00% | 10MG | $139.65 | 2021-12-16 | Buy |
| Arctom | AS025691 | Zoledronic Acid Monohydrate 98% | 50mg | $6 | 2021-12-16 | Buy |
| Arctom | AS025691 | Zoledronic Acid Monohydrate 98% | 100mg | $11 | 2021-12-16 | Buy |
| Arctom | AS025691 | Zoledronic Acid Monohydrate 98% | 250mg | $16 | 2021-12-16 | Buy |
| Arctom | AS025691 | Zoledronic Acid Monohydrate 98% | 1g | $41 | 2021-12-16 | Buy |
| Arctom | AS025691 | Zoledronic Acid Monohydrate 98% | 5g | $108 | 2021-12-16 | Buy |
| AvaChem | 1715H | Zoledronic Acid Hydrate | 100mg | $39 | 2021-12-16 | Buy |
Properties
Melting point :245 °C(dec.)
storage temp. :2-8°C
solubility :H2O: ≥2mg/mL
form :powder
color :white to beige
Merck :14,10187
InChIKey :FUXFIVRTGHOMSO-UHFFFAOYSA-N
CAS DataBase Reference :165800-06-6(CAS DataBase Reference)
storage temp. :2-8°C
solubility :H2O: ≥2mg/mL
form :powder
color :white to beige
Merck :14,10187
InChIKey :FUXFIVRTGHOMSO-UHFFFAOYSA-N
CAS DataBase Reference :165800-06-6(CAS DataBase Reference)
Safety Information
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Description
Zoledronic acid is a third-generation heterocyclic nitrogen-containing bisphosphonate that inhibits the prenylation of GTPases critical to the signaling events related to osteoclast-mediated bone resorption. It has a high affinity for hydroxyapatite (Ki = 3.47 μM) and binds directly to mineralized bone where it decreases bone resorption by inhibiting osteoclast proliferation and inducing osteoclast apoptosis. At μM concentrations, zoledronic acid demonstrates antitumor effects in vitro against breast, prostate, and myeloma cancer cells by inducing cytostasis and prevents bone metastases through its inhibitory effects on adhesion molecules, tumor cell invasion, and angiogenesis. Zoledronic acid has been used in the treatment of osteoporosis, Paget’s disease, metastatic bone disease, multiple myeloma, hypercalcemia of malignancy, and skeletal-related events associated with metastatic castrate-resistant prostate cancer.More related product prices
ACETIC ACID MELIBIOSE Folic acid CHLOROPHOSPHONAZO III 2809-21-4 Etanol Tris(2-chloroethyl) phosphate Citric acid Ethylparaben Ethyl acetate Zoledronic acid 4-Ethyl-5-fluoro-6-hydroxypyrimidine Imidazole ZOSUQUIDAR TRIHYSROCHLORIDE Zoledronate disodium tetrahydrate Azamethiphos Imidazol-1-yl-acetic acid Fenpyroximate Ethyl 1H-imidazole-1-acetateRelated product price
- ACETIC ACID
$26.8-3630.17 - MELIBIOSE
$33.2-2841.48 - Folic acid
$5-1269.63
Suppliers and manufacturers
Jinan Shengqi pharmaceutical Co,Ltd
Xiamen AmoyChem Co., Ltd
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
Antai Fine Chemical Technology Co.,Limited
Neostar United (Changzhou) Industrial Co., Ltd.
