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ChemicalBook >> CAS DataBase List >> lurasidone

lurasidone

lurasidone price.
  • $50 - $2245.7
  • Product name: lurasidone
  • CAS: 367514-87-2
  • MF: C28H36N4O2S
  • MW: 492.68
  • EINECS:696-042-8
  • MDL Number:MFCD14635357
  • Synonyms:4-{[(1R,2R)-2-{[4-(2$l^{4}-thia-6-azatricyclo[5.4.0.0^{2,6}]undeca-1(11),2,4,7,9-pentaen-5-yl)piperazin-1-yl]Methyl}cyclohexyl]Methyl}-4-azatricyclo[5.2.1.0^{2,6}]deca-1(9),2(6),7-triene-3,5-dione;lurasidone;(3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione;Lurasidone (SM13496);(3aR,4S,7R,7aS)-2-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]Methyl}cyclohexyl]Methyl}hexahydro-1H-4,7-Methanoisoindole-1,3(2H)-dione;urasidone;Lurasidone, >=98%;Lurasidone Base
19 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Chemtos
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 0.025G
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberY0344
  • Product descriptionLurasidone
  • Packaging10mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ55517
  • Product descriptionLurasidone
  • Packaging50mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ55517
  • Product descriptionLurasidone
  • Packaging100mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013701
  • Product description(3AR,4S,7R,7AS)-2-[((1R,2R)-2-[[4-(1,2-BENZISOTHIAZOL-3-YL)-PIPERAZIN-1-YL]METHYL]CYCLOHEXYL)METHYL]HEXAHYDRO-1H-4,7-METHANISOINDOL-1,3-DIONE 95.00%
  • Packaging5MG
  • Price$497.35
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013701
  • Product description(3AR,4S,7R,7AS)-2-[((1R,2R)-2-[[4-(1,2-BENZISOTHIAZOL-3-YL)-PIPERAZIN-1-YL]METHYL]CYCLOHEXYL)METHYL]HEXAHYDRO-1H-4,7-METHANISOINDOL-1,3-DIONE 95.00%
  • Packaging0.025G
  • Price$783
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154672
  • Product descriptionlurasidone >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154672
  • Product descriptionlurasidone >98%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154672
  • Product descriptionlurasidone >98%
  • Packaging1g
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000570
  • Product descriptionLurasidone ≥98%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000570
  • Product descriptionLurasidone ≥98%
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000570
  • Product descriptionLurasidone ≥98%
  • Packaging10mg
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000570
  • Product descriptionLurasidone ≥98%
  • Packaging25mg
  • Price$412
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-D0229
  • Product descriptionLurasidone 99.49%
  • Packaging10mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-D0229
  • Product descriptionLurasidone 99.49%
  • Packaging50mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-D0229
  • Product descriptionLurasidone 99.49%
  • Packaging100mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemtos
  • Product numberL-7741
  • Product descriptionLurasidoneHydrochloride
  • Packaging50mg
  • Price$1050
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0344 Lurasidone 10mg $97 2021-12-16 Buy
AK Scientific J55517 Lurasidone 50mg $120 2021-12-16 Buy
AK Scientific J55517 Lurasidone 100mg $180 2021-12-16 Buy
American Custom Chemicals Corporation API0013701 (3AR,4S,7R,7AS)-2-[((1R,2R)-2-[[4-(1,2-BENZISOTHIAZOL-3-YL)-PIPERAZIN-1-YL]METHYL]CYCLOHEXYL)METHYL]HEXAHYDRO-1H-4,7-METHANISOINDOL-1,3-DIONE 95.00% 5MG $497.35 2021-12-16 Buy
American Custom Chemicals Corporation API0013701 (3AR,4S,7R,7AS)-2-[((1R,2R)-2-[[4-(1,2-BENZISOTHIAZOL-3-YL)-PIPERAZIN-1-YL]METHYL]CYCLOHEXYL)METHYL]HEXAHYDRO-1H-4,7-METHANISOINDOL-1,3-DIONE 95.00% 0.025G $783 2021-12-16 Buy
Biorbyt Ltd orb154672 lurasidone >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb154672 lurasidone >98% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb154672 lurasidone >98% 1g $2245.7 2021-12-16 Buy
Cayman Chemical 9000570 Lurasidone ≥98% 1mg $57 2024-03-01 Buy
Cayman Chemical 9000570 Lurasidone ≥98% 5mg $193 2024-03-01 Buy
Cayman Chemical 9000570 Lurasidone ≥98% 10mg $275 2024-03-01 Buy
Cayman Chemical 9000570 Lurasidone ≥98% 25mg $412 2024-03-01 Buy
ChemScene CS-D0229 Lurasidone 99.49% 10mg $72 2021-12-16 Buy
ChemScene CS-D0229 Lurasidone 99.49% 50mg $120 2021-12-16 Buy
ChemScene CS-D0229 Lurasidone 99.49% 100mg $180 2021-12-16 Buy
Chemtos L-7741 LurasidoneHydrochloride 50mg $1050 2021-12-16 Buy

Properties

Melting point :146-149°C
Boiling point :623.4±55.0 °C(Predicted)
Density :1.273
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka :8.41±0.50(Predicted)
form :Solid
color :White to Off-White
InChIKey :PQXKDMSYBGKCJA-CVTJIBDQSA-N
SMILES :C1(=O)[C@]2([H])[C@@]([H])([C@]3([H])C[C@@]2([H])CC3)C(=O)N1C[C@@H]1CCCC[C@H]1CN1CCN(C2C3=C(SN=2)C=CC=C3)CC1
CAS DataBase Reference :367514-87-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The atypical antipsychotic lurasidone (also known as SM-13496) was approved in the United States in 2010 as an oral agent for the treatment of patients with schizophrenia. Lurasidone has potent affinity for D2 (Ki= 1.7 nM) and 5-HT2A (Ki= 2.0 nM) receptors and acts as an antagonist at both receptors. It is also a partial agonist at the 5-HT1A receptor and, unlike other atypical agents, is a potent antagonist at the 5-HT7 receptor; both of these activities are thought to confer beneficial cognitive properties. Lurasidone is further differentiated by its lack of affinity for muscarinic and histamine H1 receptors and its weak affinity for the 5-HT2C receptor. Antagonism at H1 and 5-HT2C receptors has been implicated in weight gain associated with atypical agents, while muscarinic receptor antagonism is associated with cognitive deficits.

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