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ChemicalBook CAS DataBase List 1,1-Cyclopentanedicarbonitrile
29739-46-6

1,1-Cyclopentanedicarbonitrile synthesis

2synthesis methods
-

Yield:29739-46-6 86%

Reaction Conditions:

with 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide at 80;Inert atmosphere;Cooling with ice;

References:

Van Loevezijn, Arnold;Venhorst, Jennifer;Iwema Bakker, Wouter I.;De Korte, Cor G.;De Looff, Wouter;Verhoog, Stefan;Van Wees, Jan-Willem;Van Hoeve, Martijn;Van De Woestijne, Rob P.;Van Der Neut, Martina A. W.;Borst, Alice J. M.;Van Dongen, Maria J. P.;De Bruin, Natasja M. W. J.;Keizer, Hiskias G.;Kruse, Chris G. [Journal of Medicinal Chemistry,2011,vol. 54,# 20,p. 7030 - 7054] Location in patent:experimental part