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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
187217-99-8

1-(2,2,2-TRIFLUOROETHYL)PIPERIDIN-4-AMINE synthesis

4synthesis methods
1-(2,2,2-trifluoroethyl)piperidin-4-one

81363-14-6
46 suppliers
$30.00/100mg

1-(2,2,2-TRIFLUOROETHYL)PIPERIDIN-4-AMINE

187217-99-8
26 suppliers
$130.00/50mg

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Yield:187217-99-8 70%

Reaction Conditions:

with Raney nickel in ethanol at 20; under 1551.49 - 2068.65 Torr; for 72 h;Inert atmosphere;

References:

Wityak, John;McGee, Kevin F.;Conlon, Michael P.;Song, Ren Hua;Duffy, Bryan C.;Clayton, Brent;Lynch, Michael;Wang, Gwen;Freeman, Emily;Haber, James;Kitchen, Douglas B.;Manning, David D.;Ismail, Jiffry;Khmelnitsky, Yuri;Michels, Peter;Webster, Jeff;Irigoyen, MacArena;Luche, Michele;Hultman, Monica;Bai, Mei;Kuok, Iokteng D.;Newell, Ryan;Lamers, Marieke;Leonard, Philip;Yates, Dawn;Matthews, Kim;Ongeri, Lynette;Clifton, Steve;Mead, Tania;Deupree, Susan;Wheelan, Pat;Lyons, Kathy;Wilson, Claire;Kiselyov, Alex;Toledo-Sherman, Leticia;Beconi, Maria;Mu?oz-Sanjuan, Ignacio;Bard, Jonathan;Dominguez, Celia [Journal of Medicinal Chemistry,2015,vol. 58,# 7,p. 2967 - 2987]

177-11-7 Synthesis
1,4-Dioxa-8-azaspiro[4.5]decane

177-11-7
288 suppliers
$6.00/1g

1-(2,2,2-TRIFLUOROETHYL)PIPERIDIN-4-AMINE

187217-99-8
26 suppliers
$130.00/50mg

References
8-(2,2,2-trifluoroethyl)-1,4-dioxa-8-azaspiro[4.5]decane(WXFC0424)

710350-66-6
9 suppliers
inquiry

1-(2,2,2-TRIFLUOROETHYL)PIPERIDIN-4-AMINE

187217-99-8
26 suppliers
$130.00/50mg

References
Ethanone, 1-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2,2,2-trifluoro-

176910-36-4
1 suppliers
inquiry

1-(2,2,2-TRIFLUOROETHYL)PIPERIDIN-4-AMINE

187217-99-8
26 suppliers
$130.00/50mg

References