ChemicalBook CAS DataBase List 1 2 2 6 6-PENTAMETHYL-4-PIPERIDONE 97

1 2 2 6 6-PENTAMETHYL-4-PIPERIDONE 97 synthesis

8synthesis methods

Product Name:1 2 2 6 6-PENTAMETHYL-4-PIPERIDONE 97
CAS Number:5554-54-1
Molecular formula:C10H19NO
Molecular Weight:169.26

826-36-8
300 suppliers
$6.00/5g

77-78-1
292 suppliers
$19.69/1ml

5554-54-1
73 suppliers
$60.00/100mg

Yield: 97%

Reaction Conditions:

with sodium hydroxide in N,N-dimethyl acetamide at 45; for 10 h;Temperature;Solvent;

Steps:

1-4 Example 4
n a 500ml four-necked flask equipped with a thermometer,Add 120g of 2,2,6,6-tetramethylpiperidone,DMAC300g, sodium hydroxide 100g,Install the condenser and slowly add 90g of dimethyl sulfate,And control the temperature to 45 . The addition is completed within 3 hours,Then, the reaction was continued at this temperature for 7 hours. Then cool, filter, concentrate and rectify the filtrate to obtain the final product 1,2,2,6,6-pentamethyl-4-piperidone, yield 97%.

References:

Suqian Liansheng Technology Co., Ltd.;Yuan Kaifeng;Liu Enjing;Hu Xinli;Xiang Zhanfeng CN110950794, 2020, A Location in patent:Paragraph 0025-0032

826-36-8
300 suppliers
$6.00/5g

50-00-0 Synthesis