![](/CAS/GIF/551-62-2.gif)
1,2,3,4-Tetrafluorobenzene synthesis
- Product Name:1,2,3,4-Tetrafluorobenzene
- CAS Number:551-62-2
- Molecular formula:C6H2F4
- Molecular Weight:150.07
![2,3,4,5-Tetrafluorobenzoic acid](/CAS/GIF/1201-31-6.gif)
1201-31-6
397 suppliers
$10.00/5g
![1,2,3,4-Tetrafluorobenzene](/CAS/GIF/551-62-2.gif)
551-62-2
234 suppliers
$10.00/1g
Yield:551-62-2 94.4%
Reaction Conditions:
with ammonia;copper in water at 240; for 1.25 h;Temperature;Reagent/catalyst;
Steps:
15
300 g was added to a 500 mL intermittent high pressure reaction kettleAmmonia concentration of 5g / L aqueous ammonia solution, 50g 2, 3, 4, 5-tetrafluorobenzoic acid and 1.67 g of copper powder, Heating to 240 ° C decarboxylation reaction 1. 25h; decarboxylation reaction is completed, Open the exhaust valve pressure relief, recovery of ammonia inside the kettle; cooling to room temperature, The organic phase and the aqueous phase were obtained by the separation of the filtrate and the filtrate. After the organic phase was distilled 1,2,3,4-tetrafluorobenzene 36. 5 g,was obtained by distillation. The purity of the product by HPLC was 99.1% The yield was 94.4%.
References:
Zhejiang Chemical Industry Institute Technology Co., Ltd;Zhejiang University;Fu, Jie;Mo, Jing;Lyu, Xiuyang;XU, Weiguo CN105732302, 2016, A Location in patent:Paragraph 0047; 0048
![Tetrafluorophthalic acid](/CAS/GIF/652-03-9.gif)
652-03-9
216 suppliers
$9.00/5g
![1,2,3,4-Tetrafluorobenzene](/CAS/GIF/551-62-2.gif)
551-62-2
234 suppliers
$10.00/1g
![hexafluorobenzene](/CAS/GIF/392-56-3.gif)
392-56-3
289 suppliers
$9.00/1g
![1,3,5-Trifluorobenzene](/CAS/GIF/372-38-3.gif)
372-38-3
305 suppliers
$9.00/1g
![1,2,4,5-Tetrafluorobenzene](/CAS/GIF/327-54-8.gif)
327-54-8
236 suppliers
$10.00/10g
![1,2,3,4-Tetrafluorobenzene](/CAS/GIF/551-62-2.gif)
551-62-2
234 suppliers
$10.00/1g
![hexafluorobenzene](/CAS/GIF/392-56-3.gif)
392-56-3
289 suppliers
$9.00/1g
![1,2,4,5-Tetrafluorobenzene](/CAS/GIF/327-54-8.gif)
327-54-8
236 suppliers
$10.00/10g
![1,2,3,4-Tetrafluorobenzene](/CAS/GIF/551-62-2.gif)
551-62-2
234 suppliers
$10.00/1g
![Pentafluorobenzene](/CAS/GIF/363-72-4.gif)
363-72-4
288 suppliers
$10.00/1 g
![1,2,4-Trifluorobenzene](/CAS/GIF/367-23-7.gif)
367-23-7
365 suppliers
$8.00/5g