1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride synthesis
- Product Name:1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride
- CAS Number:3459-02-7
- Molecular formula:C10H13N.ClH
- Molecular Weight:0
119-64-2
330 suppliers
$9.00/25g
3459-02-7
22 suppliers
$24.00/250mg
Yield:3459-02-7 57%
Reaction Conditions:
Stage #1: tetralinwith Benzophenone imine;copper(l) iodide;1,10-Phenanthroline;di-tert-butyl peroxide in chlorobenzene at 90; for 48 h;Inert atmosphere;Sealed tube;
Stage #2: with hydrogenchloride in methanol;water;chlorobenzene at 40; for 15 h;Inert atmosphere;Sealed tube;regioselective reaction;
References:
Kramer, S?ren [Organic Letters,2019,vol. 21,# 1,p. 65 - 69] Location in patent:supporting information