ChemicalBook CAS DataBase List 1-(2-aminoethyl)piperidin-2-one

1-(2-aminoethyl)piperidin-2-one synthesis

3synthesis methods

Product Name:1-(2-aminoethyl)piperidin-2-one
CAS Number:27578-61-6
Molecular formula:C7H14N2O
Molecular Weight:142.2

675-20-7 Synthesis

675-20-7
346 suppliers
$5.00/1g

27578-61-6
35 suppliers
$108.00/100mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 - 5 °C / Inert atmosphere
1.2: 6 h / Reflux
2.1: hydrogenchloride / methanol / 0.5 h / 0 - 5 °C / Inert atmosphere
3.1: triphenylphosphine / tetrahydrofuran / 0.5 h / 0 - 5 °C / Inert atmosphere
3.2: 2 h / 0 - 20 °C
4.1: hydrazine hydrate / methanol / 12 h / 0 - 20 °C

References:

CARMOT THERAPEUTICS, INC.;ENQUIST, Johan;KRISHNAN, Shyam;ATWAL, Suman;ERLANSON, Daniel;FUCINI, Raymond V.;HANSEN, Stig;SAWAYAMA, Andrew;SETHOFER, Steven WO2019/183577, 2019, A1

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
0 suppliers
inquiry

27578-61-6
35 suppliers
$108.00/100mg

References

3445-12-3
8 suppliers
inquiry

27578-61-6
35 suppliers
$108.00/100mg

References