ChemicalBook CAS DataBase List 1,2-Diamino-3-chlorobenzene

1,2-Diamino-3-chlorobenzene synthesis

6synthesis methods

Product Name:1,2-Diamino-3-chlorobenzene
CAS Number:21745-41-5
Molecular formula:C6H7ClN2
Molecular Weight:142.59

769-11-9 Synthesis

769-11-9
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7440-02-0 Synthesis

7440-02-0
404 suppliers
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21745-41-5
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Yield: 10.43 g (89%)

Reaction Conditions:

in ethanol;water;hydrogen

Steps:

47 3-Chloro-1,2-phenylenediamine
Example 47 3-Chloro-1,2-phenylenediamine 2-Chloro-6-nitroaniline (14.10 g, 81.71 mmol), Raney-nickel (5.02 g of a 50% slurry in water), and ethanol (200 mL) were combined in an autoclave which was pressurized to 15 psig with hydrogen. The resulting mixture was allowed to stir overnight at RT. The mixture was then filtered through a pad of celite, which was subsequently washed with several portions of methanol, and the solvents were removed by rotary evaporation to afford 10.43 g (89%) of a viscous, brown oil, which darkened upon standing. MS (EI): m/z 143.1 (M+H).

References:

Glaxo Wellcome Inc. US6204249, 2001, B1

769-11-9 Synthesis

769-11-9
146 suppliers
inquiry

21745-41-5
97 suppliers
$42.00/1 g

References

59483-54-4 Synthesis