1,2-DIBROMODODECANE synthesis

5synthesis methods

Product Name:1,2-DIBROMODODECANE
CAS Number:55334-42-4
Molecular formula:C12H24Br2
Molecular Weight:328.13

112-41-4
219 suppliers
$8.00/10g

55334-42-4
9 suppliers
inquiry

Yield:55334-42-4 97%

Reaction Conditions:

with Oxone;ammonium bromide in water;acetonitrile; for 9 h;Reflux;

Steps:

General procedure for the synthesis of dibromides:

General procedure: To a solution of olefin (2 mmol) in CH₃CN (10 mL) were added NH₄Br (4.4 mmol) and Oxone (2.2 mmol) and the mixture was stirred at reflux temperature for the time shown in Table 2. After completion (as indicated by TLC), the reaction mixture was filtered and the solvent evaporated under reduced pressure. The products were purified by column chromatography (Hexane/EtOAc, 98:2) over silica gel.

References:

MacHarla, Arun Kumar;Chozhiyath Nappunni, Rohitha;Nama, Narender [Tetrahedron Letters,2012,vol. 53,# 11,p. 1401 - 1405] Location in patent:supporting information; experimental part

2855-19-8 Synthesis