[1-(2-FLUOROPHENYL)-1-TOSYL]METHYL ISOCYANIDE synthesis
- Product Name:[1-(2-FLUOROPHENYL)-1-TOSYL]METHYL ISOCYANIDE
- CAS Number:660431-65-2
- Molecular formula:C15H12FNO2S
- Molecular Weight:289.32
536-57-2
142 suppliers
$34.00/1g
446-52-6
425 suppliers
$6.00/25g
660431-65-2
28 suppliers
$150.00/1g
Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: chloro-trimethyl-silane / acetonitrile; toluene / 4 h / 50 °C / Inert atmosphere
1.2: 24 h / 50 °C / Inert atmosphere
2.1: trichlorophosphate; triethylamine / tetrahydrofuran / 1 h / -10 °C / Inert atmosphere
References:
Fallarini;Massarotti;Gesù;Giovarruscio;Coda Zabetta;Bergo;Giannelli;Brunco;Lombardi;Sorba;Pirali [MedChemComm,2016,vol. 7,# 3,p. 409 - 419]