1-(2-oxoazepane-1-carbonyl)azepan-2-one synthesis
1synthesis methods
- Product Name:1-(2-oxoazepane-1-carbonyl)azepan-2-one
- CAS Number:19494-73-6
- Molecular formula:C13H20N2O3
- Molecular Weight:252.31
Yield:19494-73-6 77%
Reaction Conditions:
with N-ethyl-N,N-diisopropylamine in toluene;
Steps:
2 Preparation of N,N'-carbonylbis (ε-caprolactam)
EXAMPLE 2 Preparation of N,N'-carbonylbis (ε-caprolactam) The preparation is carried out as in Example 1 but using 300 ml of toluene, 0.402 mol of ε-caprolactam, 0.404 mol of DIEA and 0.21 mol of phosgene and introducing the phosgene over 30 min while maintaining the temperature of the reaction medium between 10° C. and 17° C. N,N'-Carbonylbis(ε-caprolactam) is obtained with a yield of 77% and a purity of 98% (HPLC quantitative determination).
References:
US2001/44532,2001,A1