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1-(3-(4-nitrophenoxy)propyl)pyrrolidine synthesis

3synthesis methods
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Yield:92033-81-3 100%

Reaction Conditions:

Stage #1: 3-pyrrolidin-1-yl-propan-1-olwith sodium hydroxide;N-benzyl-N,N,N-triethylammonium chloride in water;toluene at 0;
Stage #2: 4-Fluoronitrobenzene in water;toluene at 60; for 0.833333 h;

References:

WO2007/4735,2007,A1 Location in patent:Page/Page column 10