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1-(3-chlorophenyl)-2-methylpropan-2-ol synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: thionyl chloride / 3 h / 90 °C / Inert atmosphere; Schlenk technique
2: tetrahydrofuran / 0 - 20 °C / Inert atmosphere; Schlenk technique

References:

Xu, Wentao;Ma, Junyang;Yuan, Xiang-Ai;Dai, Jie;Xie, Jin;Zhu, Chengjian [Angewandte Chemie - International Edition,2018,vol. 57,# 32,p. 10357 - 10361][Angew. Chem.,2018,vol. 130,p. 10514 - 10518,5]