1-(3-fluoro-5-Methoxyphenyl)piperazine synthesis
1synthesis methods
- Product Name:1-(3-fluoro-5-Methoxyphenyl)piperazine
- CAS Number:1121613-65-7
- Molecular formula:C11H15FN2O
- Molecular Weight:210.25
Yield:1121613-65-7 39%
Reaction Conditions:
with dichlorobis(tri-O-tolylphosphine)palladium;sodium t-butanolate in toluene at 100;
References:
Leopoldo, Marcello;Lacivita, Enza;De Giorgio, Paola;Contino, Marialessandra;Berardi, Francesco;Perrone, Roberto [Bioorganic and Medicinal Chemistry,2009,vol. 17,# 2,p. 758 - 766] Location in patent:experimental part