1-(3-Thienyl)butane-1,2-dione synthesis
1synthesis methods
- Product Name:1-(3-Thienyl)butane-1,2-dione
- CAS Number:1421479-06-2
- Molecular formula:C8H8O2S
- Molecular Weight:168.21
Yield:1421479-06-2 49%
Reaction Conditions:
Stage #1: 3-thiophene carboxaldehyde;propionaldehydewith 3,4-dimethyl-5-(2-hydroxyethyl)thiazolium iodide;triethylamineInert atmosphere;
Stage #2: with bismuth(III) oxide;acetic acidInert atmosphere;
References:
Schüttler, Christian;Li-B?hmer, Zhen;Harms, Klaus;Von Zezschwitz, Paultheo [Organic Letters,2013,vol. 15,# 4,p. 800 - 803] Location in patent:supporting information