ChemicalBook CAS DataBase List 1-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)ETHAN-1-ONE

1-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)ETHAN-1-ONE synthesis

2synthesis methods

Product Name:1-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)ETHAN-1-ONE
CAS Number:15221-84-8
Molecular formula:C15H13ClO
Molecular Weight:244.72

99-91-2 Synthesis

99-91-2
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108-88-3
7 suppliers
$14.00/100ml

1-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)ETHAN-1-ONE

15221-84-8
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Yield:15221-84-8 57%

Reaction Conditions:

Stage #1: toluenewith thianthrene-5-oxide;trifluoromethylsulfonic anhydride in acetonitrile at -20 - 20; for 0.666667 h;Inert atmosphere;Schlenk technique;
Stage #2: para-chloroacetophenonewith palladium diacetate;cesium fluoride;XPhos in N,N-dimethyl-formamide;acetonitrile at 80; for 11 h;Inert atmosphere;Schlenk technique;

References:

Huang, Yu-Hao;Nie, Xiao-Xue;Wang, Peng [Organic Letters,2020,vol. 22,# 19,p. 7716 - 7720] Location in patent:supporting information

108-90-7
644 suppliers
$10.00/25G

35675-44-6
34 suppliers
$38.00/250mg

15221-84-8
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References

1-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)ETHAN-1-ONE Related Search:

1-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)ETHANE-1,2-DIONE 4'-Chloroacetophenone 4'-Chloro-2-phenylacetophenone 4-METHYLPHENYLACETONE 4'-Chloropropiophenone