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[1,4]Diazepane-5-carboxylic acid tert-butyl ester synthesis

2synthesis methods
1H-1,4-Diazepine-5-carboxylic acid, hexahydro-1,4-bis(phenylmethyl)-, 1,1-dimethylethyl ester

138883-21-3
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[1,4]Diazepane-5-carboxylic acid tert-butyl ester

138883-20-2
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Yield:138883-20-2 80%

Reaction Conditions:

with hydrogen;palladium on activated charcoal in ethanol; under 760 Torr;Ambient temperature;

References:

Barraclough, Paul;Farrant, R. Duncan;Kettle, Dianne;Smith, Steven [Journal of Chemical Research, Miniprint,1991,# 11,p. 2876 - 2884]