![](/CAS/GIF/100-25-4.gif)
1,4-DINITROBENZENE synthesis
- Product Name:1,4-DINITROBENZENE
- CAS Number:100-25-4
- Molecular formula:C6H4N2O4
- Molecular Weight:168.11
![p-Phenylenediamine](/CAS/GIF/106-50-3.gif)
106-50-3
604 suppliers
$19.00/25g
![1,4-DINITROBENZENE](/CAS/GIF/100-25-4.gif)
100-25-4
4 suppliers
$46.00/5g
Yield:100-25-4 77%
Reaction Conditions:
with trifluoroacetyl peroxide in dichloromethane at -5 - 5; for 1 h;
Steps:
2
Add a peroxytrifluoroacetic acid solution to the reaction vessel, lower the temperature to -5 to 5 ° C, add 381.7g (3.53mol) of p-aminoaniline, keep the temperature at -5 to 5 ° C, and stir the reaction for 1 hour. After the reaction, add 2L of water and stir , The layers were left to stand, and the organic layer was washed with 2L saturated sodium bisulfite solution, 2L saturated sodium bicarbonate solution, and water to pH 7-8, and the solvent was distilled off under reduced pressure. Dichloromethane and methanol (dichloromethane and The volume ratio of methanol was 1: 2) The solution was recrystallized to obtain 456.9 g (yield 77%) of the product as a yellow solid p-nitronitrobenzene
References:
Chongqing Pharmaceutical College;Liu Dianqing;He Dongxian;Wang Kun;Guo Shengchao;Wang Guangming CN110330432, 2019, A Location in patent:Paragraph 0025; 0029
![Nitrobenzene](/CAS/GIF/98-95-3.gif)
98-95-3
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$14.00/25g
![1,4-DINITROBENZENE](/CAS/GIF/100-25-4.gif)
100-25-4
4 suppliers
$46.00/5g
![4-Nitroaniline](/CAS/GIF/100-01-6.gif)
100-01-6
10 suppliers
$11.19/25G
![1,4-DINITROBENZENE](/CAS/GIF/100-25-4.gif)
100-25-4
4 suppliers
$46.00/5g
![1,4-Phenylenebisboronic acid](/CAS/GIF/4612-26-4.gif)
4612-26-4
285 suppliers
$6.00/1g
![1,4-DINITROBENZENE](/CAS/GIF/100-25-4.gif)
100-25-4
4 suppliers
$46.00/5g
![N,N-DIMETHYL-4-NITROANILINE](/CAS/GIF/100-23-2.gif)
100-23-2
6 suppliers
$36.00/5g
![1,4-DINITROBENZENE](/CAS/GIF/100-25-4.gif)
100-25-4
4 suppliers
$46.00/5g