ChemicalBook CAS DataBase List 1-(4-FLUOROBENZYL)CYCLOPROPANECARBOXYLIC ACID

1-(4-FLUOROBENZYL)CYCLOPROPANECARBOXYLIC ACID synthesis

2synthesis methods

Product Name:1-(4-FLUOROBENZYL)CYCLOPROPANECARBOXYLIC ACID
CAS Number:139229-60-0
Molecular formula:C11H11FO2
Molecular Weight:194.2

Cyclopropanecarboxylic acid, 1-[(4-fluorophenyl)methyl]-, 1,1-dimethylethyl ester

139229-59-7
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1-(4-FLUOROBENZYL)CYCLOPROPANECARBOXYLIC ACID

139229-60-0
24 suppliers
$265.00/100mg

Yield:139229-60-0 90%

Reaction Conditions:

with trifluoroacetic acid

Steps:

10 1-(4-Fluorobenzyl)-cyclopropanecarboxylic acid STR30

1-(4-Fluorobenzyl)-cyclopropanecarboxylic acid STR30 25.0 g (0.10 mol) of tert-butyl 1-(4-fluoro-benzyl)-cyclopropanecarboxylate (prepared according to Intermediate 10a) were reacted with 14.3 g (0.13 mol) of trifluoroacetic acid, similarly to Intermediate 1c. Yield: 90%; colorless oil.

References:

US5371268,1994,A

459-46-1
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$10.00/1g

139229-60-0
24 suppliers
$265.00/100mg

References