1-(4-Nitrophenyl)-1H-pyrrole-2-carboxylic acid synthesis

2synthesis methods

Product Name:1-(4-Nitrophenyl)-1H-pyrrole-2-carboxylic acid
CAS Number:82552-86-1
Molecular formula:C11H8N2O4
Molecular Weight:232.19

methyl 1-(4-nitrophenyl)-1H-pyrrole-2-carboxylate

124475-67-8
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1-(4-Nitrophenyl)-1H-pyrrole-2-carboxylic acid

82552-86-1
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Yield:82552-86-1 96%

Reaction Conditions:

Stage #1: 1-(4-nitrophenyl)-pyrrole-2-carboxylic acid methyl esterwith water;sodium hydroxide in tetrahydrofuran;methanol at 23 - 50;
Stage #2: with hydrogenchloride in tetrahydrofuran;methanol;water at 23;

References:

Bilodeau, Francois;Brochu, Marie-Christine;Guimond, Nicolas;Thesen, Kris H.;Forgione, Pat [Journal of Organic Chemistry,2010,vol. 75,# 5,p. 1550 - 1560] Location in patent:experimental part

30186-41-5 Synthesis

1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE

30186-41-5
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$30.00/20mg

82552-86-1
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References