1-(5-AMINO-2-PYRIDINYL)-3-(S)-PYRROLIDINOL synthesis
- Product Name:1-(5-AMINO-2-PYRIDINYL)-3-(S)-PYRROLIDINOL
- CAS Number:939376-61-1
- Molecular formula:C9H13N3O
- Molecular Weight:179.22
1233859-93-2
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$350.00/1g
939376-61-1
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$180.00/250MG
Yield:939376-61-1 99%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in methanol at 23; for 1 h;
Steps:
125.2 Step 2:
(S)-1-(5-Nitropyridin-2-yl)pyrrolidin-3-ol (574 mg, 2.74 mmol) was dissolved in methanol. 10 % Pd / C (115 mg) was added to it. The resulting mixture was stirred at room temperature under hydrogen atmosphere for 1 h. The mixture was filtered through celite bed and the filtrate was concentrated under reduced pressure to afford (S)-1-(5-aminopyridin-2- yl)pyrrolidin-3-ol (491 mg, 99 %).
References:
WO2013/13815,2013,A1 Location in patent:Page/Page column 197
5418-51-9
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939376-61-1
13 suppliers
$180.00/250MG
4548-45-2
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939376-61-1
13 suppliers
$180.00/250MG