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ChemicalBook CAS DataBase List 1,5-diphenylpenta-1,4-diyn-3-ol
15814-32-1

1,5-diphenylpenta-1,4-diyn-3-ol synthesis

11synthesis methods
-

Yield:15814-32-1 87%

Reaction Conditions:

Stage #1: phenylacetylenewith ethylmagnesium bromide in tetrahydrofuran at 0 - 20; for 1 h;Inert atmosphere;
Stage #2: formic acid ethyl ester in tetrahydrofuran at 0 - 20; for 1 h;Inert atmosphere;

References:

Liu, Yuanhong;Lu, Mingduo;Wang, Ali;Xie, Xin [Organic Letters,2022,vol. 24,# 15,p. 2944 - 2949] Location in patent:supporting information